Abstract

Scope of Work Dr. Todd Golub - Core A: DMA Microarray/Bioinformatics Core This core will perform gene microarray profiling on samples as well as catalog and analyze all the profiling data. This includes, but is not limited to sample preparation, microarray preparation and all laboratory work including quality control, data analysis and distribution of data.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA092625-09
Application #
7896692
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
9
Fiscal Year
2009
Total Cost
$388,748
Indirect Cost

  Institution

Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Chapuy, Bjoern; Cheng, Hongwei; Watahiki, Akira et al. (2016) Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease. Blood 127:2203-13
Zhang, Baochun; Calado, Dinis Pedro; Wang, Zhe et al. (2015) An oncogenic role for alternative NF-?B signaling in DLBCL revealed upon deregulated BCL6 expression. Cell Rep 11:715-26
Carey, Christopher D; Gusenleitner, Daniel; Chapuy, Bjoern et al. (2015) Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens. J Mol Diagn 17:19-30
Gostissa, Monica; Bianco, Julia M; Malkin, Daniel J et al. (2013) Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas. Proc Natl Acad Sci U S A 110:2934-9
Yan, Qingsheng; Xu, Rong; Zhu, Liya et al. (2013) BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8. Mol Cell Biol 33:845-57
Ying, Carol Y; Dominguez-Sola, David; Fabi, Melissa et al. (2013) MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma. Nat Immunol 14:1084-92
Chen, Linfeng; Monti, Stefano; Juszczynski, Przemyslaw et al. (2013) SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas. Cancer Cell 23:826-38
Rossi, Davide; Rasi, Silvia; Spina, Valeria et al. (2013) Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia. Blood 121:1403-12
Caro, Pilar; Kishan, Amar U; Norberg, Erik et al. (2012) Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell 22:547-60
Sander, Sandrine; Calado, Dinis P; Srinivasan, Lakshmi et al. (2012) Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis. Cancer Cell 22:167-79

Showing the most recent 10 out of 124 publications