The Administrative Core will provide support for each of the Projects of this P01, as well as the Metabolism/Histopathology Core (Core B).
The aims of the Administrative Core are to ensure that the resources within the P01 are distributed equitably to the investigators and all rules and regulations of the National Cancer Institute and the National Institutes of Health are followed. The Administrative Core will coordinate monthly meetings of the investigators and their laboratories, and facilitate communication between our investigators and the External Advisory Board. The Administrative Core will also coordinate the quarterly regional meetings held at Princeton University and hosted by Dr. Joshua Rabinowitz. Finally, the Administrative Core will work with the business administration office of the Abramson Family Cancer Research Institute (AFCRI) to ensure that funds are subcontracted to Memorial Sloan-Kettering Cancer Center (MSKCC) for Project 1 led by Dr. Craig Thompson. The finances of the P01 will be organized by Mr. James Riley, the AFCRI Director of Fiscal Operations, who will meet monthly with the P01 PI and quarterly with each Project and Core Leader. Ms. Dana Opiela will coordinate travel arrangements for the members of the P01, as well as the advisors who will visit U. Pennsylvania. Furthermore, Ms. Jaclyn Regan will coordinate travel arrangements for the members of the P01 located at MSKCC. Both Ms. Opiela and Ms. Regan will provide administrative support for each of the P01 investigators for efforts related to the program. It is anticipated that through the combined efforts of the Core Director (Dr. Simon), Mr. Riley, Ms. Opiela, and Ms. Regan that the research effort of this P01 will run with optimum efficiency.

Public Health Relevance

As PI of this Program Project application, Dr. Celeste Simon will work closely with Ms. Dana Opiela, Administrative Assistant to this core. Moreover, Dr. Simon and Ms. Opiela will co-ordinate activities of the Program with Mr. Jim Riley, Director of Fiscal Operations at the Abramson Family Cancer Research Institute at the University of Pennsylvania, and Ms. Jaclyn Regan, laboratory Administrative Assistant to Drs. Craig Thompson and Tulia Lindsten at Memorial Sloan-Kettering Cancer Center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA104838-11
Application #
8742518
Study Section
Special Emphasis Panel (ZCA1-RPRB-J (M1))
Project Start
2003-12-01
Project End
2019-08-31
Budget Start
2014-09-17
Budget End
2015-08-31
Support Year
11
Fiscal Year
2014
Total Cost
$112,302
Indirect Cost
$63,204
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Sanchez, Danielle J; Steger, David J; Skuli, Nicolas et al. (2018) PPAR? is dispensable for clear cell renal cell carcinoma progression. Mol Metab 14:139-149
Hong, Feng; Liu, Bei; Wu, Bill X et al. (2017) CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response. Nat Struct Mol Biol 24:834-839
Rozpedek, W; Nowak, A; Pytel, D et al. (2017) Molecular Basis of Human Diseases and Targeted Therapy Based on Small-Molecule Inhibitors of ER Stress-Induced Signaling Pathways. Curr Mol Med 17:118-132
Gade, Terence P F; Tucker, Elizabeth; Nakazawa, Michael S et al. (2017) Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Radiology 283:702-710

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