Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA109552-02
Application #
7550522
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
2
Fiscal Year
2006
Total Cost
$377,705
Indirect Cost
Name
Translational Genomics Research Institute
Department
Type
DUNS #
118069611
City
Phoenix
State
AZ
Country
United States
Zip Code
85004
Grandjean, Geoffrey; de Jong, Petrus R; James, Brian et al. (2016) Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1? Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target. Cancer Res 76:4259-4269
Samulitis, Betty K; Pond, Kelvin W; Pond, Erika et al. (2015) Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors. Cancer Biol Ther 16:43-51
Sinha, Arkadeep; Cherba, David; Bartlam, Heather et al. (2014) Mesenchymal-like pancreatic cancer cells harbor specific genomic alterations more frequently than their epithelial-like counterparts. Mol Oncol 8:1253-65
Dorr, Robert T; Samulitis, Betty K; Wisner, Lee et al. (2013) Characterization of a membrane-active anti-tumor agent, UA8967. Invest New Drugs 31:576-86
Landowski, Terry H; Samulitis, Betty K; Dorr, Robert T (2013) The diaryl oxazole PC-046 is a tubulin-binding agent with experimental anti-tumor efficacy in hematologic cancers. Invest New Drugs 31:1616-25
Whatcott, Clifford; Han, Haiyong; Posner, Richard G et al. (2013) Tumor-stromal interactions in pancreatic cancer. Crit Rev Oncog 18:135-51
Spivak-Kroizman, Taly R; Hostetter, Galen; Posner, Richard et al. (2013) Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer. Cancer Res 73:3235-47
Liang, Winnie S; Craig, David W; Carpten, John et al. (2012) Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing. PLoS One 7:e43192
Provenzano, Paolo P; Cuevas, Carlos; Chang, Amy E et al. (2012) Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 21:418-29
Xie, Lifang; Kassner, Michelle; Munoz, Ruben M et al. (2012) Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors. Biochem Pharmacol 83:452-61

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