Abstract

The Statistics & Database Core facility will provide the statistical and database support for all research? conducted in the Program Project. It will include collaboration and consultation on the statistical aspects of? study design and planning, database development and maintenance, data quality control and monitoring,? and analysis and interpretation of data.
Specific aims are to provide: Ready and dedicated access to statistical and database expertise to investigators, Statistical expertise for the planning, conduct, analysis and reporting of pre-clinical, correlative and clinical studies, Consultation to investigators and data collectors (technicians, nurses, data managers) in forms design, data collection, records abstraction and data entry, Development and maintenance of a database for storing data collected by investigators, Development and implementation of plans for data management, quality control, data audit and study monitoring, Scientific computing facility to meet the statistical and database requirements for research, including technical assistance for data sharing between projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA111519-03
Application #
7678541
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
3
Fiscal Year
2008
Total Cost
$315,696
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Sykes, Megan (2018) Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol 79:334-342
La Muraglia 2nd, G M; O'Neil, M J; Madariaga, M L et al. (2015) A novel approach to measuring cell-mediated lympholysis using quantitative flow and imaging cytometry. J Immunol Methods 427:85-93
Li, Hao Wei; Andreola, Giovanna; Carlson, Alicia L et al. (2015) Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. J Immunol 195:1282-92
Matar, Abraham J; Patil, Aarti R; Al-Musa, Ahmad et al. (2015) Effect of Irradiation on Incidence of Post-Transplant Lymphoproliferative Disorder after Hematopoietic Cell Transplantation in Miniature Swine. Biol Blood Marrow Transplant 21:1732-8
Sykes, M (2015) Immune tolerance in recipients of combined haploidentical bone marrow and kidney transplantation. Bone Marrow Transplant 50 Suppl 2:S82-6
Duran-Struuck, Raimon; Huang, Christene A; Orf, Katherine et al. (2015) Miniature Swine as a Clinically Relevant Model of Graft-Versus-Host Disease. Comp Med 65:429-43
Buchan, Sarah; Manzo, Teresa; Flutter, Barry et al. (2015) OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J Immunol 194:125-133
Wang, Hui; Yang, Yong-Guang (2014) The complex and central role of interferon-? in graft-versus-host disease and graft-versus-tumor activity. Immunol Rev 258:30-44
Leonard, D A; Kurtz, J M; Mallard, C et al. (2014) Vascularized composite allograft tolerance across MHC barriers in a large animal model. Am J Transplant 14:343-55
Wang, Yi; Wang, Hui; Xia, Jinxing et al. (2013) Activated CD8 T cells acquire NK1.1 expression and preferentially locate in the liver in mice after allogeneic hematopoietic cell transplantation. Immunol Lett 150:75-8

Showing the most recent 10 out of 36 publications