The Protein Biochemistry Core will provide state-of-the-art technical support in protein expression andpurification, protein-protein interaction studies, immunoprecipitation, and enzymatic assays germane for theresearch goals being pursued in individual projects. By centralizing these services under the leadership oftwo experienced investigators, Patrick Sung (Core Director) and Steven Raynard (Core Co-ordinator), theProtein Biochemistry Core will enhance the productivity of program project members and promote synergyamong the different projects by streamlining access of critical reagents and methodologies acrosslaboratories.Following established protocols, the Protein Biochemistry Core personnel will carry out protein expression inbacteria, yeast, or insect cells and protein purification. Moreover, the Core will work with the participatinglaboratories to develop new protein expression and purification procedures. To help meet new challenges ofthe program, the Core Director and Core Co-ordinator will consult with program members on matterspertaining to protein-protein interaction studies, immunoprecipitation, and the development of enzymeassays.
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