The sharing of strengths encouraged by the Program Project funding mechanism provides for greater opportunities andcapabilities through the unification of a shared commitment to a central hypothetical question than would exist for anyof the scientists involved in the Proposal individually. The main goal of the Administrative Core of this Proposal is tofacilitate and support the unification and interaction of the scientists and administrative personnel working on the fourProjects and two Cores from The Rockefeller University and Yale University that comprise this Proposal.
Specific Aims. Aim I. Coordination and communication between the Cores and Projects in the ProposalFacilitate communication between the four Projects, two Cores and two institutionsSchedule all formal meetingsFacilitate the transfer of information for data sharing and manuscript generationCareer development coordination center for students and postdoctoral traineesAim II. Maintenance of the Physical Working Space, Supplies and Equipment for the Scientific Core andProjects I, II and IV of the ProposalMaintenance of the physical laboratory and administrative space at RockefellerOversight of the laboratory safety guidelinesPurchase of and maintenance of supply stocksAim III. Data and Progress Record Maintenance and Clerical Support for the ProposalClerical support and record maintenanceMaintenance of project-generated resources filesPublication generation and archive for the ProposalSupply and equipment record maintenance for the Scientific Core and Projects I, II and IVBudget tracking and allocation for the Cores and ProjectsData Sharing, Biological material resources and tools generated by the Program Project Grant

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
5P01DA010044-13
Application #
7700064
Study Section
Special Emphasis Panel (ZDA1-RXL-E (18))
Project Start
2008-02-01
Project End
2011-01-31
Budget Start
2008-02-01
Budget End
2009-01-31
Support Year
13
Fiscal Year
2008
Total Cost
$33,323
Indirect Cost
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Li, Daniel; Musante, Veronica; Zhou, Wenliang et al. (2018) Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. J Biol Chem 293:11179-11194
Seo, J-S; Zhong, P; Liu, A et al. (2018) Elevation of p11 in lateral habenula mediates depression-like behavior. Mol Psychiatry 23:1113-1119
Madero-Pérez, Jesús; Fdez, Elena; Fernández, Belén et al. (2018) Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Mol Neurodegener 13:3
Chang, Audrey N; Gao, Ning; Liu, Zhenan et al. (2018) The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1c?, is essential for smooth muscle contraction. J Biol Chem 293:16677-16686
Ceglia, Ilaria; Lee, Ko-Woon; Cahill, Michael E et al. (2017) WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proc Natl Acad Sci U S A 114:1395-1400
Seo, J-S; Wei, J; Qin, L et al. (2017) Cellular and molecular basis for stress-induced depression. Mol Psychiatry 22:1440-1447
Nishi, Akinori; Matamales, Miriam; Musante, Veronica et al. (2017) Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution. J Biol Chem 292:1462-1476
Andrade, Erika C; Musante, Veronica; Horiuchi, Atsuko et al. (2017) ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase). J Neurosci 37:2709-2722
Musante, Veronica; Li, Lu; Kanyo, Jean et al. (2017) Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Elife 6:
Milosevic, Ana; Liebmann, Thomas; Knudsen, Margarete et al. (2017) Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain. J Comp Neurol 525:955-975

Showing the most recent 10 out of 205 publications