This research aims to characterize the speech production of postlingually deafened adults before and after they receive cochlear implants, in order to (a) help evaluate and improve prostheses and (b) constrain models of the role of hearing in speech production. Toward these ends, we have been making longitudinal measures of speech acoustics, respiration and vocal- fold contact area (with electroglottography - EGG). Our work to data has shown that: there are a number of abnormalities pre-implant; changes occur in all parameters measured thus far upon activation of the speech processor over long and short time spans; many of those changes are in the direction of normalcy; and there are relations among the parameters that can guide us in a principled account of the mechanisms underlying most of the changes, whether or not they are in the direction of normalcy. There are also differences among parameters in the timing of changes measured longitudinally which, despite differences among subjects, will contribute to our understanding of the role of hearing in speech production. In this second phase of the program project grant, we will continue to use a within-subject longitudinal design as well as paradigms in which we modify the characteristics of the processor stimulation several times during a single experimental session. In both types of experiment, we will expand the parameters studied to include measures of intonation, period-to-period variability in FO, consonant acoustics, instantaneous airflow during consonant articulation, nasalization, glottal waveform measures, and measures of inter-articulator timing. We will compare suprasegmental measures of deficits in patients' speech perception with anomalies in their speech production. The stimulation modification paradigm will be elaborated to include alterations of auditory stimulation characteristics such as spectral slope, to test specific hypotheses about relations between production and perception. The results of this latter type of experiment may lead to hypotheses about sub-phonemic perceptual mechanisms, which we will also test.

Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Massachusetts Eye and Ear Infirmary
Department
Type
DUNS #
073825945
City
Boston
State
MA
Country
United States
Zip Code
02114
Hickok, Gregory (2009) Eight problems for the mirror neuron theory of action understanding in monkeys and humans. J Cogn Neurosci 21:1229-43
Litvak, Leonid M; Delgutte, Bertrand; Eddington, Donald K (2003) Improved temporal coding of sinusoids in electric stimulation of the auditory nerve using desynchronizing pulse trains. J Acoust Soc Am 114:2079-98
Litvak, Leonid; Delgutte, Bertrand; Eddington, Donald (2003) Improved neural representation of vowels in electric stimulation using desynchronizing pulse trains. J Acoust Soc Am 114:2099-111
Litvak, Leonid M; Smith, Zachary M; Delgutte, Bertrand et al. (2003) Desynchronization of electrically evoked auditory-nerve activity by high-frequency pulse trains of long duration. J Acoust Soc Am 114:2066-78
Litvak, L; Delgutte, B; Eddington, D (2001) Auditory nerve fiber responses to electric stimulation: modulated and unmodulated pulse trains. J Acoust Soc Am 110:368-79
White, J A; Burgess, B J; Hall, R D et al. (2000) Pattern of degeneration of the spiral ganglion cell and its processes in the C57BL/6J mouse. Hear Res 141:8-Dec
Incesulu, A; Nadol Jr, J B (1998) Correlation of acoustic threshold measures and spiral ganglion cell survival in severe to profound sensorineural hearing loss: implications for cochlear implantation. Ann Otol Rhinol Laryngol 107:906-11
Uchanski, R M; Braida, L D (1998) Effects of token variability on our ability to distinguish between vowels. Percept Psychophys 60:533-43
Nadol Jr, J B (1997) Patterns of neural degeneration in the human cochlea and auditory nerve: implications for cochlear implantation. Otolaryngol Head Neck Surg 117:220-8
Rabinowitz, W M; Eddington, D K (1995) Effects of channel-to-electrode mappings on speech reception with the ineraid cochlear implant. Ear Hear 16:450-8

Showing the most recent 10 out of 22 publications