Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK062345-05
Application #
7499416
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (M4))
Project Start
2007-08-01
Project End
2008-07-31
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
5
Fiscal Year
2007
Total Cost
$131,384
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Wilson, Patricia D (2016) Therapeutic targets for polycystic kidney disease. Expert Opin Ther Targets 20:35-45
Allen, Mark D; Qamar, Seema; Vadivelu, Murali K et al. (2014) A high-resolution structure of the EF-hand domain of human polycystin-2. Protein Sci 23:1301-8
Norman, Jill (2011) Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD). Biochim Biophys Acta 1812:1327-36
Elliott, Justine; Zheleznova, Nadezhda N; Wilson, Patricia D (2011) c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation. Am J Physiol Cell Physiol 301:C522-9
Zheleznova, Nadezhda N; Wilson, Patricia D; Staruschenko, Alexander (2011) Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells. Biochim Biophys Acta 1812:1301-13
Boucher, Catherine A; Ward, Heather H; Case, Ruth L et al. (2011) Receptor protein tyrosine phosphatases are novel components of a polycystin complex. Biochim Biophys Acta 1812:1225-38
Li, Xiaohong; Iomini, Carlo; Hyink, Deborah et al. (2011) PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation. Dev Biol 356:475-85
Zeltner, N; Kohlbrenner, E; Clément, N et al. (2010) Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors. Gene Ther 17:872-9
Nadella, Rama; Blumer, Joe B; Jia, Guangfu et al. (2010) Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD. J Am Soc Nephrol 21:1275-80
Dere, Ruhee; Wilson, Patricia D; Sandford, Richard N et al. (2010) Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR. PLoS One 5:e9239

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