Abstract

Public Health Relevance

These experiments will integrate the the interactions among biomarkers of susceptibility, exposure, and response to OP compounds during critical periods of development. Using MS analysis of modified APH and BChE to examine the role of genetic variability of P0N1 in modulating gene environment interactions will provide a more detailed understanding of the role of P0N1 in modulating environmental exposures to OPs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
2P01ES009601-11
Application #
7853482
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Project Start
Project End
Budget Start
2009-09-25
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$68,119
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Ulrich, Angie; Molina, Yamile; Briant, Katherine J et al. (2018) Stress Among Latinos: Does it Vary by Occupation and Agricultural Season? J Occup Environ Med 60:810-814
Griffith, William C; Vigoren, Eric M; Smith, Marissa N et al. (2018) Application of improved approach to evaluate a community intervention to reduce exposure of young children living in farmworker households to organophosphate pesticides. J Expo Sci Environ Epidemiol :
Plascak, Jesse J; Griffith, William C; Workman, Tomomi et al. (2018) Evaluation of the relationship between residential orchard density and dimethyl organophosphate pesticide residues in house dust. J Expo Sci Environ Epidemiol :
Tamaro, Catherine M; Smith, Marissa N; Workman, Tomomi et al. (2018) Characterization of organophosphate pesticides in urine and home environment dust in an agricultural community. Biomarkers 23:174-187
Gibbs, Jenna L; Yost, Michael G; Negrete, Maria et al. (2017) Passive Sampling for Indoor and Outdoor Exposures to Chlorpyrifos, Azinphos-Methyl, and Oxygen Analogs in a Rural Agricultural Community. Environ Health Perspect 125:333-341
Smith, Marissa N; Workman, Tomomi; McDonald, Katie M et al. (2017) Seasonal and occupational trends of five organophosphate pesticides in house dust. J Expo Sci Environ Epidemiol 27:372-378
Stanaway, Ian B; Wallace, James C; Shojaie, Ali et al. (2017) Human Oral Buccal Microbiomes Are Associated with Farmworker Status and Azinphos-Methyl Agricultural Pesticide Exposure. Appl Environ Microbiol 83:
Shaffer, Rachel M; Smith, Marissa N; Faustman, Elaine M (2017) Developing the Regulatory Utility of the Exposome: Mapping Exposures for Risk Assessment through Lifestage Exposome Snapshots (LEnS). Environ Health Perspect 125:085003
Peter, Beate; Wijsman, Ellen M; Nato Jr, Alejandro Q et al. (2016) Genetic Candidate Variants in Two Multigenerational Families with Childhood Apraxia of Speech. PLoS One 11:e0153864
Kim, Hee Yeon; Wegner, Susanna H; Van Ness, Kirk P et al. (2016) Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells. Reprod Toxicol 65:212-223

Showing the most recent 10 out of 109 publications