Public Health Relevance

This study will examine several endocrine disrupting and neurotoxic chemicals to which children living in California agricultural communities may be highly exposed: DDT, Mn, and PBDEs. These exposures have relevance beyond farmworker children: PBDE exposure is ubiquitous in the US, Mn is widely used as a fuel additive and in fungicides, and DDT use is increasing globally for malaria control. We will address key data gaps on the human health effects of these compounds crucial for assessing public health costs and benefits.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
3P01ES009605-11S1
Application #
7938153
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Program Officer
Kirshner, Annette G
Project Start
1998-11-01
Project End
2014-07-31
Budget Start
2009-09-24
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$493,000
Indirect Cost
Name
University of California Berkeley
Department
Type
Schools of Public Health
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
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Sjödin, Andreas; Jones, Richard S; Gunier, Robert B et al. (2018) Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, and 2,2-Bis(4-chlorophenyl)-1,1-dichloroethene in 7- and 9-Year-Old Children and Their Mothers in the Center for the Health Assessment of Mothers and Children of Salinas Cohort. Environ Sci Technol 52:2287-2294
Huen, Karen; Solomon, Olivia; Kogut, Katherine et al. (2018) PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure. Environ Int 121:31-40
Sagiv, Sharon K; Harris, Maria H; Gunier, Robert B et al. (2018) Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture. Environ Health Perspect 126:047012
Torres, Jacqueline M; Deardorff, Julianna; Gunier, Robert B et al. (2018) Worry About Deportation and Cardiovascular Disease Risk Factors Among Adult Women: The Center for the Health Assessment of Mothers and Children of Salinas Study. Ann Behav Med 52:186-193

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