Public Health Relevance

The purpose of this project is to assess exposures to persistent contaminants present in homes that may cause leukemia, based upon analysis of house dust, blood collected at the time of the diagnosis of leukemia cases, and archived newborn dried blood spots collected at birth.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
1P01ES018172-01
Application #
7852185
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Project Start
2009-09-25
Project End
2014-07-31
Budget Start
2009-09-25
Budget End
2010-07-31
Support Year
1
Fiscal Year
2009
Total Cost
$122,849
Indirect Cost
Name
University of California Berkeley
Department
Type
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Rappaport, Stephen M (2018) Redefining environmental exposure for disease etiology. NPJ Syst Biol Appl 4:30
de Smith, Adam J; Walsh, Kyle M; Francis, Stephen S et al. (2018) BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia. Int J Cancer 143:2647-2658
Edmands, William M B; Hayes, Josie; Rappaport, Stephen M (2018) SimExTargId: a comprehensive package for real-time LC-MS data acquisition and analysis. Bioinformatics 34:3589-3590
Felix, Janine F; Joubert, Bonnie R; Baccarelli, Andrea A et al. (2018) Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol 47:22-23u
Wallace, Amelia D; Francis, Stephen S; Shao, Xiaorong et al. (2018) A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology. Haematologica 103:e29-e31
Wiemels, Joseph L; Walsh, Kyle M; de Smith, Adam J et al. (2018) GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Nat Commun 9:286
Petridou, Eleni Th; Georgakis, Marios K; Erdmann, Friederike et al. (2018) Advanced parental age as risk factor for childhood acute lymphoblastic leukemia: results from studies of the Childhood Leukemia International Consortium. Eur J Epidemiol :
Wang, Rong; Metayer, Catherine; Morimoto, Libby et al. (2017) Parental Age and Risk of Pediatric Cancer in the Offspring: A Population-Based Record-Linkage Study in California. Am J Epidemiol 186:843-856
de Smith, Adam J; Kaur, Maneet; Gonseth, Semira et al. (2017) Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia. Cancer Res 77:1674-1683
Petrick, Lauren; Edmands, William; Schiffman, Courtney et al. (2017) An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies. Metabolomics 13:

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