Wang, Louise Z; Kenyon, George L; Johnson, Kenneth A (2004) Novel mechanism of inhibition of HIV-1 reverse transcriptase by a new non-nucleoside analog, KM-1. J Biol Chem 279:38424-32
|
Makino, S; Ewing, T J; Kuntz, I D (1999) DREAM++: flexible docking program for virtual combinatorial libraries. J Comput Aided Mol Des 13:513-32
|
Rose, R B; Craik, C S; Stroud, R M (1998) Domain flexibility in retroviral proteases: structural implications for drug resistant mutations. Biochemistry 37:2607-21
|
Sun, Y; Ewing, T J; Skillman, A G et al. (1998) CombiDOCK: structure-based combinatorial docking and library design. J Comput Aided Mol Des 12:597-604
|
Oshiro, C M; Kuntz, I D (1998) Characterization of receptors with a new negative image: use in molecular docking and lead optimization. Proteins 30:321-36
|
Friedman, S H; Ganapathi, P S; Rubin, Y et al. (1998) Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation. J Med Chem 41:2424-9
|
Radmer, R J; Kollman, P A (1998) The application of three approximate free energy calculations methods to structure based ligand design: trypsin and its complex with inhibitors. J Comput Aided Mol Des 12:215-27
|
Craik, C S; Babe, L M; Dauber, D et al. (1998) Engineering catalytically defective forms of HIV protease to modulate its activity. Adv Exp Med Biol 436:31-9
|
Gaur, M; Leavitt, A D (1998) Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation. J Virol 72:4678-85
|
Dauber, D S; McPhee, F; Unal, A et al. (1998) Optimization of a macromolecular inhibitor of HIV-1 protease. Adv Exp Med Biol 436:65-70
|
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