Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM047525-05
Application #
2184986
Study Section
Special Emphasis Panel (SRC (02))
Project Start
1992-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1998-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Physiology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Shen, Y M; Chertihin, O I; Biltonen, R L et al. (1999) Lipid-dependent activation of protein kinase C-alpha by normal alcohols. J Biol Chem 274:34036-44
Cafiso, D S (1998) Dipole potentials and spontaneous curvature: membrane properties that could mediate anesthesia. Toxicol Lett 100-101:431-9
Hodges, M W; Cafiso, D S; Polnaszek, C F et al. (1997) Water translational motion at the bilayer interface: an NMR relaxation dispersion measurement. Biophys J 73:2575-9
North, C; Cafiso, D S (1997) Contrasting membrane localization and behavior of halogenated cyclobutanes that follow or violate the Meyer-Overton hypothesis of general anesthetic potency. Biophys J 72:1754-61
Qin, Z; Wertz, S L; Jacob, J et al. (1996) Defining protein-protein interactions using site-directed spin-labeling: the binding of protein kinase C substrates to calmodulin. Biochemistry 35:13272-6
Olins, A L; Olins, D E; Bazett-Jones, D P (1996) Osmium ammine-B and electron spectroscopic imaging of ribonucleoproteins: correlation of stain and phosphorus. Biol Cell 87:143-7
Dibble, A R; Hinderliter, A K; Sando, J J et al. (1996) Lipid lateral heterogeneity in phosphatidylcholine/phosphatidylserine/diacylglycerol vesicles and its influence on protein kinase C activation. Biophys J 71:1877-90
Qin, Z; Cafiso, D S (1996) Membrane structure of protein kinase C and calmodulin binding domain of myristoylated alanine rich C kinase substrate determined by site-directed spin labeling. Biochemistry 35:2917-25
Magyar, J; Szabo, G (1996) Effects of volatile anesthetics on the G protein-regulated muscarinic potassium channel. Mol Pharmacol 50:1520-8
Baber, J; Ellena, J F; Cafiso, D S (1995) Distribution of general anesthetics in phospholipid bilayers determined using 2H NMR and 1H-1H NOE spectroscopy. Biochemistry 34:6533-9

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