Abstract

Data Analysis Core. The Data Analysis Core facility will provide the software and hardware support for the Program. It includes support for Dr. H. Li, who will perform specialized programming, coordinate the network used by members of the Program, and maintain the computer facilities. It also includes costs for supplies and equipment contracts for this effort.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM047969-09
Application #
6338824
Study Section
Project Start
2000-08-01
Project End
2001-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
9
Fiscal Year
2000
Total Cost
$127,296
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Budelier, Melissa M; Cheng, Wayland W L; Bergdoll, Lucie et al. (2017) Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1. J Biol Chem 292:9294-9304
Jiang, Xiaoping; Shu, Hong-Jin; Krishnan, Kathiresan et al. (2016) A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition. Neuropharmacology 108:193-206
Zhou, Yu; Xia, Xiao-Ming; Lingle, Christopher J (2015) Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implications. Proc Natl Acad Sci U S A 112:5237-42
Li, Ping; Akk, Gustav (2015) Synaptic-type ?1?2?2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs. Mol Pharmacol 87:776-81
Purgert, Carolyn A; Izumi, Yukitoshi; Jong, Yuh-Jiin I et al. (2014) Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus. J Neurosci 34:4589-98
Bandari, Suman; Chakraborty, Hirak; Covey, Douglas F et al. (2014) Membrane dipole potential is sensitive to cholesterol stereospecificity: implications for receptor function. Chem Phys Lipids 184:25-9
Eaton, Megan M; Lim, You Bin; Covey, Douglas F et al. (2014) Modulation of the human ?1 GABAA receptor by inhibitory steroids. Psychopharmacology (Berl) 231:3467-78
Zolkowska, Dorota; Dhir, Ashish; Krishnan, Kathiresan et al. (2014) Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology (Berl) 231:3325-32
Drews, A; Mohr, F; Rizun, O et al. (2014) Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels. Br J Pharmacol 171:1019-32
Qian, Mingxing; Krishnan, Kathiresan; Kudova, Eva et al. (2014) Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of ?-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone. J Med Chem 57:171-90

Showing the most recent 10 out of 193 publications