(taken from the application). The continued operation of the previously funded Protein Synthesis Core is proposed. This facility will provide designed experimental material for the work detailed in Projects 1, 2, 2I and V. The core consists of an Applied Biosystems Model 433A solid-phase peptide synthesizer, a Beckman System Gold HPLC instrument, and a proposed UV/Vis spectrometer. Salary is requested for a dedicated Research Specialist who will maintain and operate the core.
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Okuno, Toshiaki; Koutsogiannaki, Sophia; Ohba, Mai et al. (2017) Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production. FASEB J 31:1584-1594 |
Granata, Daniele; Ponzoni, Luca; Micheletti, Cristian et al. (2017) Patterns of coevolving amino acids unveil structural and dynamical domains. Proc Natl Acad Sci U S A 114:E10612-E10621 |
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