Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
1P01GM066312-01A2
Application #
6861517
Study Section
Special Emphasis Panel (ZGM1-TB-6 (04))
Project Start
2004-07-01
Project End
2009-06-30
Budget Start
2004-07-01
Budget End
2005-07-31
Support Year
1
Fiscal Year
2004
Total Cost
$335,233
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
Yamamoto, Yusuke; Sousse, Linda E; Enkhbaatar, Perenlei et al. (2012) ?-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model. Shock 38:671-6
Maybauer, Marc O; Maybauer, Dirk M; Fraser, John F et al. (2012) Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis. Shock 37:170-6
Yamamoto, Yusuke; Enkhbaatar, Perenlei; Sousse, Linda E et al. (2012) Nebulization with ?-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model. Shock 37:408-14
Lange, Matthias; Hamahata, Atsumori; Traber, Daniel L et al. (2012) Pulmonary microvascular hyperpermeability and expression of vascular endothelial growth factor in smoke inhalation- and pneumonia-induced acute lung injury. Burns 38:1072-8
Yamamoto, Yusuke; Enkhbaatar, Perenlei; Sakurai, Hiroyuki et al. (2012) Development of a long-term ovine model of cutaneous burn and smoke inhalation injury and the effects of early excision and skin autografting. Burns 38:908-16
Hamahata, Atsumori; Enkhbaatar, Perenlei; Lange, Matthias et al. (2012) Administration of a peroxynitrite decomposition catalyst into the bronchial artery attenuates pulmonary dysfunction after smoke inhalation and burn injury in sheep. Shock 38:543-8
Rehberg, Sebastian; Yamamoto, Yusuke; Sousse, Linda et al. (2012) Selective V(1a) agonism attenuates vascular dysfunction and fluid accumulation in ovine severe sepsis. Am J Physiol Heart Circ Physiol 303:H1245-54
Hamahata, Atsumori; Enkhbaatar, Perenlei; Lange, Matthias et al. (2012) Administration of poly(ADP-ribose) polymerase inhibitor into bronchial artery attenuates pulmonary pathophysiology after smoke inhalation and burn in an ovine model. Burns 38:1210-5
Lange, Matthias; Hamahata, Atsumori; Traber, Daniel L et al. (2011) Preclinical evaluation of epinephrine nebulization to reduce airway hyperemia and improve oxygenation after smoke inhalation injury. Crit Care Med 39:718-24
Sousse, Linda E; Yamamoto, Yusuke; Enkhbaatar, Perenlei et al. (2011) Acute lung injury-induced collagen deposition is associated with elevated asymmetric dimethylarginine and arginase activity. Shock 35:282-8

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