Trajectories of risk and resilience represent contrasting pathways from early adolescence to young adulthood.Persistent social disadvantage and continuing patterns of maladaptive behavior in adolescence tend to negativelyaffect health and well-being in the young adult years through impaired education, unstable relationships and work.Even so, adolescents at risk frequently manage to find escape routes to greater opportunity and positive adaptations,whereas other youth lose the advantage of their social origins and become increasingly at risk. Little is known aboutthe contextual, behavioral, and biological mechanisms by which trajectories of risk shape health and well-beinginto the young adult years, or about the mechanisms by which young people escape from the risk process totrajectories of resilience, especially minorities. Using panel data from Add Health, subproject n proposes a researchplan defined by three interrelated objectives that are consistent with the integrative life course theoretical frameworkof the Program Project: (1) to interrelate risk trajectories based upon sequences of contextual, behavioral, andbiological risk factors-the life course, and patterns of health from adolescence into young adulthood, with emphasison their linking mechanisms; (2) to investigate mechanisms that enhance a trajectory of resilience from adolescentadversity into the 30s, including individual resources, social support and life transitions; and (3) to assess thegenerality of these life patterns by social contexts, subpopulations, including the genetics subsample. The data willcome from Add Health's in-school survey (Wave I in-home interview with Ss & caregiver (1995), Waves n (1996)and HI (2001/2002), and Wave IV, a proposed interview with Ss in 2007-2008. Collaborations are planned withthe Harris subproject on family formation trajectories and with the Williams, Hewitt, and Guo subprojects on theassessment of gene-environment effects on risk-resilience and health, and on young adult biomarkers of distress.Modes of data analysis will be contingent on the specific question and available data, but the research plan callsfor both variable-based and person-centered strategies, including standard linear regression, and latent growth andmixture models.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD031921-13
Application #
7718272
Study Section
Special Emphasis Panel (ZRG1-HOP-B (40))
Project Start
2008-01-01
Project End
2010-12-31
Budget Start
2008-01-01
Budget End
2008-12-31
Support Year
13
Fiscal Year
2008
Total Cost
$2,970,123
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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