A Program Project, MANAGEMENT OF CHRONIC PAIN IN REHABILITATION,is proposed to initiate a systemic program of multidisciplinary research investigating the nature, scope, and management of chronic pain problems in individuals with spinal cord injury, amputation, and cerebral palsy.
The specific aims of the Program Project are: 1. (a) To determine the frequency and types of chronic pain experienced by persons after spinal cord injury; and (b) to examine the efficacy of specific a pharmacological treatment (oral amitriptyline) compared to placebo in reducing pain and disability and improving functional capacity in persons with spinal cord injury (Project I). 2. (a) To determine the prevalence and types of chronic pain experience by persons with cerebral palsy; and (b) to examine the associations between specific pain coping responses and subsequent pain and functioning in individuals with cerebral palsy (Project II). 3. (a) To examine the efficacy of pre-amputation analgesia on the incidence of phantom limb and stump pain following amputation; (b) to determine the frequency and types of chronic pain experienced by persons with acquired amputation: and (c) to examine the efficacy of a specific pharmacological treatment (oral amitriptyline) compared to placebo in reducing pain and disability and improving functional capacity in persons with chronic pain associated with amputation (Project III). 4. In support of these research, a scientific core will provide centralized support services for scientific communication, statistical consultation, data management, measure development, and preparation of reports and manuscripts. The scientific core will also examine and refine a biopsychosocial model of chronic pain as it applies to individuals with physical disabilities both within and across each study group. Scientific Core personnel will also perform interviews with select study participants to determine: (1) the qualitative nature of chronic pain problems for specific individuals, (2) the effects of pain on the participants' lives, and (3) the impact of the interventions on each individual's life. This broad-based research project will enhance our understanding of the chronic pain problems in individuals with physical disabilities, and will also, for the first time, provide examinations of pain treatment interventions that have been recommended for the treatment of these pain problems.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD033988-04
Application #
2889246
Study Section
Special Emphasis Panel (SRC (PM))
Program Officer
Quatrano, Louis A
Project Start
1996-08-25
Project End
2001-07-31
Budget Start
1999-08-01
Budget End
2000-07-31
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Washington
Department
Physical Medicine & Rehab
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Miró, Jordi; de la Vega, Rocío; Gertz, Kevin J et al. (2017) The role of perceived family social support and parental solicitous responses in adjustment to bothersome pain in young people with physical disabilities. Disabil Rehabil :1-8
Jensen, Mark P; Tomé-Pires, Catarina; de la Vega, Rocío et al. (2017) What Determines Whether a Pain is Rated as Mild, Moderate, or Severe? The Importance of Pain Beliefs and Pain Interference. Clin J Pain 33:414-421
Miró, Jordi; de la Vega, Rocío; Solé, Ester et al. (2017) Defining mild, moderate, and severe pain in young people with physical disabilities. Disabil Rehabil 39:1131-1135
Miró, Jordi; Solé, Ester; Gertz, Kevin et al. (2017) Pain Beliefs and Quality of Life in Young People With Disabilities and Bothersome Pain. Clin J Pain 33:998-1005
Miró, J; Castarlenas, E; de la Vega, R et al. (2016) Validity of three rating scales for measuring pain intensity in youths with physical disabilities. Eur J Pain 20:130-7
de la Vega, Rocío; Racine, Mélanie; Sánchez-Rodríguez, Elisabet et al. (2016) Psychometric properties of the short form of the Children's Depression Inventory (CDI-S) in young people with physical disabilities. J Psychosom Res 90:57-61
Kratz, Anna L; Ehde, Dawn M; Hanley, Marisol A et al. (2016) Cross-Sectional Examination of the Associations Between Symptoms, Community Integration, and Mental Health in Multiple Sclerosis. Arch Phys Med Rehabil 97:386-94
Raichle, Katherine A; Osborne, Travis L; Jensen, Mark P et al. (2015) Preoperative state anxiety, acute postoperative pain, and analgesic use in persons undergoing lower limb amputation. Clin J Pain 31:699-706
Ehde, Dawn M; Alschuler, Kevin N; Osborne, Travis L et al. (2015) Utilization and patients' perceptions of the effectiveness of pain treatments in multiple sclerosis: A cross-sectional survey. Disabil Health J 8:452-6
Miró, Jordi; Gertz, Kevin J; Carter, Gregory T et al. (2014) Pain location and intensity impacts function in persons with myotonic dystrophy type 1 and facioscapulohumeral dystrophy with chronic pain. Muscle Nerve 49:900-5

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