Early behavioral interventions for young children with autism have relied on direct training of skills through operant conditioning and modeling. These interventions have reported moderate success in improving cognitive, social and language skills, increasing peer interactions and reducing maladaptive behaviors. Yet few programs have addressed certain core features of autism, namely joint attention and symbolic play abilities. Productive language skills at age 5-6 continue to be the single best predictor of positive outcome for individuals with autism, and joint attention skills (e.g., pointing, showing, coordinate attention) are important predictors of language ability in young children with autism. Thus, the major goal of the proposed project is to facilitate improvements in joint attention skills among young children with autism. Participants will be 40 children with autism between 2 and 4 years of age attending an intensive day-treatment early childhood program, and their primary caregivers. Two difference systematic, targeted interventions will be delivered daily with randomly selected children and their caregivers. One intervention will aim to improve play skills the other on increasing joint attention skills and affective sharing in social interactions. Daily interventions will continue throughout the length of the day-treatment program, approximately 3-4 months. Several developmental assessments will be collected with children at per- intervention, during intervention and post-discharge at 6 and 12 months. Growth modeling techniques will be employed to assess intervention effects over time. It is predicted that the targeted joint attention intervention will result specifically in improvements in the initiation of joint attention, and that joint attention will continue to predict to language skills at follow-up.

Project Start
1999-02-16
Project End
1999-05-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Freeman, Stephanny F N; Gulsrud, Amanda; Kasari, Connie (2015) Brief Report: Linking Early Joint Attention and Play Abilities to Later Reports of Friendships for Children with ASD. J Autism Dev Disord 45:2259-66
Siller, Michael; Swanson, Meghan; Gerber, Alan et al. (2014) A parent-mediated intervention that targets responsive parental behaviors increases attachment behaviors in children with ASD: results from a randomized clinical trial. J Autism Dev Disord 44:1720-32
Gulsrud, Amanda C; Hellemann, Gerhard S; Freeman, Stephanny F N et al. (2014) Two to ten years: developmental trajectories of joint attention in children with ASD who received targeted social communication interventions. Autism Res 7:207-15
Siller, Michael; Hutman, Ted; Sigman, Marian (2013) A parent-mediated intervention to increase responsive parental behaviors and child communication in children with ASD: a randomized clinical trial. J Autism Dev Disord 43:540-55
Lawton, Kathy; Kasari, Connie (2012) Brief report: longitudinal improvements in the quality of joint attention in preschool children with autism. J Autism Dev Disord 42:307-12
Davies, Mari S; Dapretto, Mirella; Sigman, Marian et al. (2011) Neural bases of gaze and emotion processing in children with autism spectrum disorders. Brain Behav 1:1-11
Scott-Van Zeeland, Ashley A; Dapretto, Mirella; Ghahremani, Dara G et al. (2010) Reward processing in autism. Autism Res 3:53-67
Hogart, Amber; Wu, David; LaSalle, Janine M et al. (2010) The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13. Neurobiol Dis 38:181-91
Scott-Van Zeeland, Ashley A; McNealy, Kristin; Wang, A Ting et al. (2010) No neural evidence of statistical learning during exposure to artificial languages in children with autism spectrum disorders. Biol Psychiatry 68:345-51
Scott-Van Zeeland, Ashley A; Abrahams, Brett S; Alvarez-Retuerto, Ana I et al. (2010) Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2. Sci Transl Med 2:56ra80

Showing the most recent 10 out of 15 publications