Abstract

The purpose of the Patient Coordination and Assessment Core Module (PCACM-CORE B) is to facilitate the participation of human subjects in Program Project research, in particular, Projects I and II.
Specific aims are as follows:
Aim 1 : To provide assessment, eligibility determination, and enrollment of potential participants into Project 1 (neurobehavioral project) and Project II (neuroimaging project);
Aim 2 : To recruit potential participants for the Program project, while maintaining and expanding liaison with community agencies such as parent groups, mental health agencies, and schools, in order to increase the participant recruitment base for this program of research;
Aim 3 : Maintain participant enrollment in the Program project and prevent attrition.
Aim 4 : Collect clinical data for comparison with data from Projects I and II;
Aim 5 : Provide culturally-based translation of parent-report measures to allow participation of children from Spanish-speaking families and other minority individuals in protocols. The PCACM will serve as a central mechanism for the management of all aspects of human subjects' participation including screening, enrollment, scheduling, transitions between projects, problem resolution, and oversight of informed consent and human subjects protection.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
1P01HD035471-01A1
Application #
6108887
Study Section
Project Start
1999-03-01
Project End
2000-02-29
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Texas Health Science Center Houston
Department
Type
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225

  Publications

Ahlgrim, Nathan S; Raper, Jessica; Johnson, Emily et al. (2017) Neonatal perirhinal cortex lesions impair monkeys' ability to modulate their emotional responses. Behav Neurosci 131:359-71
Raper, Jessica; Wilson, Mark; Sanchez, Mar et al. (2017) Increased anxiety-like behaviors, but blunted cortisol stress response after neonatal hippocampal lesions in monkeys. Psychoneuroendocrinology 76:57-66
Payne, Christa; Cirilli, Laetitia; Bachevalier, Jocelyne (2017) An MRI study of the corpus callosum in monkeys: Developmental trajectories and effects of neonatal hippocampal and amygdala lesions. Dev Psychobiol 59:495-506
Malkova, Ludise; Alvarado, Maria C; Bachevalier, Jocelyne (2016) Effects of Separate or Combined Neonatal Damage to the Orbital Frontal Cortex and the Inferior Convexity on Object Recognition in Monkeys. Cereb Cortex 26:618-27
Alvarado, Maria C; Malkova, Ludise; Bachevalier, Jocelyne (2016) Development of relational memory processes in monkeys. Dev Cogn Neurosci 22:27-35
Dickerson, Aisha S; Pearson, Deborah A; Loveland, Katherine A et al. (2014) Role of parental occupation in autism spectrum disorder diagnosis and severity. Res Autism Spectr Disord 8:997-1007
Heuer, Eric; Bachevalier, Jocelyne (2013) Working memory for temporal order is impaired after selective neonatal hippocampal lesions in adult rhesus macaques. Behav Brain Res 239:55-62
Kazama, Am; Bachevalier, J (2013) Effects of Selective Neonatal Amygdala Damage on Concurrent Discrimination Learning and Reinforcer Devaluation in Monkeys. J Psychol Psychother Suppl 7:5
Coskun, Mehmet Akif; Loveland, Katherine A; Pearson, Deborah A et al. (2013) Functional assays of local connectivity in the somatosensory cortex of individuals with autism. Autism Res 6:190-200
Raper, Jessica; Wilson, Mark; Sanchez, Mar et al. (2013) Pervasive alterations of emotional and neuroendocrine responses to an acute stressor after neonatal amygdala lesions in rhesus monkeys. Psychoneuroendocrinology 38:1021-35

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