Abstract

Outline of Core Activities I. To deliver a robust physical activity promotion intervention to asthmatic and obese adolescents. The intervention will be: a. Grounded in behavioral theory b. Modeled after successful intervention programs c. Tailored to the needs and abilities of study participants II. To monitor and quantify the dose of and adherence to the intervention a. Document frequency, intensity and duration of participant exercise b. Employ both observational and objective methods c. Track and record barriers to adherence d. Monitor diet over the course of the training intervention using food recall with NDS-R We will utilize a special one-hour session, minimum of 3-session/week, small group afterschool program designed specifically for the PPG. A carefully selected and skilled PE Teacher will train 6-8 students (including participants from Projects I and II, and control children) per session to help meet their special physical activity needs. The trainer will be assisted by a Teacher's Aide. As outlined below, we have selected for this study a frequency, dose, and duration of physical activity that is likely to have measurable effects on physiological and body composition measurements of physical fitness.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
2P01HD048721-06A1
Application #
8248434
Study Section
Pediatrics Subcommittee (CHHD)
Project Start
Project End
Budget Start
2012-01-02
Budget End
2012-12-31
Support Year
6
Fiscal Year
2012
Total Cost
$164,277
Indirect Cost
$57,066

  Institution

Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Maharaj, Sheena; Lu, Kim D; Radom-Aizik, Shlomit et al. (2018) Inter- and intra-subject variability of nitric oxide levels in leukocyte subpopulations. Nitric Oxide 72:41-45
Radom-Aizik, Shlomit; Zaldivar, Frank P; Nance, Dwight M et al. (2018) A Translational Model of Incomplete Catch-Up Growth: Early-Life Hypoxia and the Effect of Physical Activity. Clin Transl Sci 11:412-419
Lu, Kim D; Cooper, Dan; Haddad, Fadia et al. (2017) Glucocorticoid receptor expression on circulating leukocytes in healthy and asthmatic adolescents in response to exercise. Pediatr Res 82:261-271
Lu, Kim D; Radom-Aizik, Shlomit; Haddad, Fadia et al. (2017) Glucocorticoid receptor expression on circulating leukocytes differs between healthy male and female adults. J Clin Transl Sci 1:108-114
Galant, Stanley P; Komarow, Hirsh D; Shin, Hye-Won et al. (2017) The case for impulse oscillometry in the management of asthma in children and adults. Ann Allergy Asthma Immunol 118:664-671
Lakes, Kimberley D; Guo, Yuqing; Lucas, Candice Taylor et al. (2017) Measuring Maternal Behaviors in the Neonatal Intensive Care Unit. Infants Young Child 30:124-132
Tran, Brian D; Chiu, Abraham; Tran, Charlene et al. (2016) Exercise and Repeated Testing Improves Accuracy of Laser Doppler Assessment of Microvascular Function Following Shortened (1-minute) Blood Flow Occlusion. Microcirculation 23:293-300
Lu, Kim D; Billimek, John; Bar-Yoseph, Ronen et al. (2016) Sex Differences in the Relationship between Fitness and Obesity on Risk for Asthma in Adolescents. J Pediatr 176:36-42
Cooper, Dan M; Leu, Szu-Yun; Taylor-Lucas, Candice et al. (2016) Cardiopulmonary Exercise Testing in Children and Adolescents with High Body Mass Index. Pediatr Exerc Sci 28:98-108
Lu, Kim D; Manoukian, Krikor; Radom-Aizik, Shlomit et al. (2016) Obesity, Asthma, and Exercise in Child and Adolescent Health. Pediatr Exerc Sci 28:264-274

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