Overview of Research Core UnitThe Zebrafish Genetics Core is critical to all three Component Projects (CPs). It will provide state-of-the-artresources for working with wildtype and mutant zebrafish lines, and generate the embryos to be analyzed inthe three CPs. It will allow the participating investigators to maintain existing wildtype and mutant lines; generatenew mutant lines by mutagenesis followed by phenotypic or sequence-based screening; propagate andscreen families harboring new mutations; and preserve lines by sperm cryopreservation. It will provide facilitiesfor handling all of the wildtype and mutant crosses for the three CPs, as well as for initial phenotypic analyses.The facility is housed in a newly-renovated 2800 sq ft facility. The Facility Director is a Ph.D. scientist withextensive experience in research and in management of research facilities. She will be assisted by an AssistantManager who is expert in zebrafish care, a full-time technician responsible for the maintenance of theaquaculture system, and by several helpers who will handle daily animal husbandry including feeding, tankcleaning, etc.
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