Abstract

The aim of the tissue core is to provide a morphology service to all projects and to support the breeding and maintenance of the mice. All projects in this proposal will require extensive use of morphological techniques to meet their goals, and it is cost effective to allocate these duties to a core. The second function of this Core is to establish and maintain a facility that allows the breeding of mice (wild type, chimera, and transgenics) and we propose to use one skilled technician to carry out all these tasks. Again it is core cost effective to have these duties controlled by the core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL003174-47
Application #
6575715
Study Section
Project Start
2002-03-01
Project End
2003-02-28
Budget Start
Budget End
Support Year
47
Fiscal Year
2002
Total Cost
$65,394
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Qin, Wan; Roberts, Meredith A; Qi, Xiaoli et al. (2016) Depth-resolved 3D visualization of coronary microvasculature with optical microangiography. Phys Med Biol 61:7536-7550
Mahoney Jr, William M; Fleming, Jo Nadine; Schwartz, Stephen M (2011) A unifying hypothesis for scleroderma: identifying a target cell for scleroderma. Curr Rheumatol Rep 13:28-36
Paige, Sharon L; Osugi, Tomoaki; Afanasiev, Olga K et al. (2010) Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS One 5:e11134
Nourse, Marilyn B; Halpin, Daniel E; Scatena, Marta et al. (2010) VEGF induces differentiation of functional endothelium from human embryonic stem cells: implications for tissue engineering. Arterioscler Thromb Vasc Biol 30:80-9
Naumova, Anna V; Reinecke, Hans; Yarnykh, Vasily et al. (2010) Ferritin overexpression for noninvasive magnetic resonance imaging-based tracking of stem cells transplanted into the heart. Mol Imaging 9:201-10
Minami, Elina; Castellani, Chiara; Malchodi, Laura et al. (2010) The role of macrophage-derived urokinase plasminogen activator in myocardial infarct repair: urokinase attenuates ventricular remodeling. J Mol Cell Cardiol 49:516-24
Moreno-Gonzalez, Alicia; Korte, F Steven; Dai, Jin et al. (2009) Cell therapy enhances function of remote non-infarcted myocardium. J Mol Cell Cardiol 47:603-13
Anderl, Jeff N; Robey, Thomas E; Stayton, Patrick S et al. (2009) Retention and biodistribution of microspheres injected into ischemic myocardium. J Biomed Mater Res A 88:704-10
Stevens, K R; Kreutziger, K L; Dupras, S K et al. (2009) Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci U S A 106:16568-73
Stevens, Kelly R; Pabon, Lil; Muskheli, Veronica et al. (2009) Scaffold-free human cardiac tissue patch created from embryonic stem cells. Tissue Eng Part A 15:1211-22

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