Abstract

This Core provides: (a) a wide range of histologic and cytologic services; (b) photographic and digital imaging and analysis; and, (c) professional consultation to research faculty and students and fellows in their laboratories. The Core also keeps abreast of new developments in histopathology and helps participating faculty apply the appropriate techniques to their research projects. Finally, the Core helps the project leaders prepare images for publication and presentation. This Core provides: (a) a wide range of histologic and cytologic services; (b) photographic and digital imaging and analysis; and, (c) professional consultation to research faculty and students and fellows in their laboratories. The Core also keeps abreast of new developments in histopathology and helps participating faculty apply the appropriate techniques to their research projects. Finally, the Core helps the project leaders prepare images for publication and presentation.Financial support for this Core arises entirely from investigator initiated research grants. It is thus a shared resource, with staff support based on the needs of the individual investigators. This PPG provides partial (approximately 1/3) support of the facilities and personnel in this Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL010342-41
Application #
7615629
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
41
Fiscal Year
2008
Total Cost
$167,800
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Han, Liang; Limjunyawong, Nathachit; Ru, Fei et al. (2018) Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness. Nat Neurosci 21:324-328
Hallowell, R W; Collins, S L; Craig, J M et al. (2017) mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis. Nat Commun 8:14208
Moldobaeva, Aigul; Jenkins, John; Zhong, Qiong et al. (2017) Lymphangiogenesis in rat asthma model. Angiogenesis 20:73-84
Craig, John M; Scott, Alan L; Mitzner, Wayne (2017) Immune-mediated inflammation in the pathogenesis of emphysema: insights from mouse models. Cell Tissue Res 367:591-605
Oh, Min-Hee; Collins, Samuel L; Sun, Im-Hong et al. (2017) mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages. Cell Rep 20:2439-2454
Lagassé, H A Daniel; Anidi, Ifeanyi U; Craig, John M et al. (2016) Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes. J Leukoc Biol 99:659-71
Lin, Amanda H Y; Shang, Yan; Mitzner, Wayne et al. (2016) Aberrant DNA Methylation of Phosphodiesterase [corrected] 4D Alters Airway Smooth Muscle Cell Phenotypes. Am J Respir Cell Mol Biol 54:241-9
Zhong, Qiong; Jenkins, John; Moldobaeva, Aigul et al. (2016) Effector T Cells and Ischemia-Induced Systemic Angiogenesis in the Lung. Am J Respir Cell Mol Biol 54:394-401
Vigeland, Christine L; Collins, Samuel L; Chan-Li, Yee et al. (2016) Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased ?? T Cells. PLoS One 11:e0163288
D'Alessio, F R; Craig, J M; Singer, B D et al. (2016) Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming. Am J Physiol Lung Cell Mol Physiol 310:L733-46

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