Abstract

The function of this core is to provide histopathological, immunohistochemical, in situ hybridization, ultrastructural, ultrastructural morphologic, and quantitative morphological support to the research projects from a central core facility. This facility provides an environment where studies are performed in a uniform manner allowing for better quality control. This leads to an overall conservation of resources by avoiding redundancy of supplies and equipment in the individual projects. The interaction of the morphology core personnel with each investigator will also facilitate communication regarding the development of techniques and regarding each project's morphological findings. This will lead to increased efficiency and conservation of monies in each project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL036577-16
Application #
6494831
Study Section
Project Start
1986-07-01
Project End
2006-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
16
Fiscal Year
2001
Total Cost
$186,552
Indirect Cost

  Institution

Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206

  Publications

Takeda, Katsuyuki; Webb, Tracy L; Ning, Fangkun et al. (2018) Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation. J Immunol 200:1261-1269
Wang, Meiqin; Yang, Ivana V; Davidson, Elizabeth J et al. (2018) Forkhead box protein 3 demethylation is associated with tolerance induction in peanut-induced intestinal allergy. J Allergy Clin Immunol 141:659-670.e2
Gelfand, Erwin W; Joetham, Anthony; Wang, Meiqin et al. (2017) Spectrum of T-lymphocyte activities regulating allergic lung inflammation. Immunol Rev 278:63-86
Gelfand, Erwin W (2017) Importance of the leukotriene B4-BLT1 and LTB4-BLT2 pathways in asthma. Semin Immunol 33:44-51
Takeda, Katsuyuki; Miyahara, Nobuaki; Matsubara, Shigeki et al. (2016) Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation. Immune Netw 16:165-75
Schedel, Michaela; Jia, Yi; Michel, Sven et al. (2016) 1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. Nat Commun 7:10213
Wang, M; Han, J; Domenico, J et al. (2016) Combined blockade of the histamine H1 and H4 receptor suppresses peanut-induced intestinal anaphylaxis by regulating dendritic cell function. Allergy 71:1561-1574
Goleva, Elena; Covar, Ronina; Martin, Richard J et al. (2016) Corticosteroid pharmacokinetic abnormalities in overweight and obese corticosteroid resistant asthmatics. J Allergy Clin Immunol Pract 4:357-60.e2
Medda, Rituparna; Lyros, Orestis; Schmidt, Jamie L et al. (2015) Anti inflammatory and anti angiogenic effect of black raspberry extract on human esophageal and intestinal microvascular endothelial cells. Microvasc Res 97:167-80
Li, Ling-Bo; Leung, Donald Y M; Goleva, Elena (2015) Activated p38 MAPK in Peripheral Blood Monocytes of Steroid Resistant Asthmatics. PLoS One 10:e0141909

Showing the most recent 10 out of 471 publications