Abstract

The Shared Instrumentation Core has been supported by the PPG from its inception and includes the following laboratories: Molecular Biology Laboratory-Oligonucleotide synthesis and DNA sequencing Protein Chemistry Laboratory-Synthesis, purification, analysis, and post-synthesis modification of peptides Flow Cytometry Laboratory-Fluorescence-based cell sorting and analysis Biophysics Laboratory-Biomolecular interaction analysis, spectrofluorometry, and fluorescence analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL044612-11
Application #
6332547
Study Section
Project Start
2000-07-18
Project End
2001-04-30
Budget Start
Budget End
Support Year
11
Fiscal Year
2000
Total Cost
$273,227
Indirect Cost

  Institution

Name
Bloodcenter of Wisconsin, Inc.
Department
Type
DUNS #
City
Milwaukee
State
WI
Country
United States
Zip Code
53233

  Publications

Zeng, Hu; Yu, Mei; Tan, Haiyan et al. (2018) Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. Sci Adv 4:eaar5701
Kanaji, Sachiko; Orje, Jennifer N; Kanaji, Taisuke et al. (2018) Humanized GPIb?-von Willebrand factor interaction in the mouse. Blood Adv 2:2522-2532
Baumgartner, C K; Mattson, J G; Weiler, H et al. (2017) Targeting factor VIII expression to platelets for hemophilia A gene therapy does not induce an apparent thrombotic risk in mice. J Thromb Haemost 15:98-109
Zhang, Nanyan; Zhi, Huiying; Curtis, Brian R et al. (2016) CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes. Blood 127:675-80
Chen, Yuhong; Zheng, Yongwei; You, Xiaona et al. (2016) Kras Is Critical for B Cell Lymphopoiesis. J Immunol 196:1678-85
Newman, Debra K; Fu, Guoping; Adams, Tamara et al. (2016) The adhesion molecule PECAM-1 enhances the TGF-?-mediated inhibition of T cell function. Sci Signal 9:ra27
Chen, Yingyu; Schroeder, Jocelyn A; Chen, Juan et al. (2016) The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity. Blood 127:1346-54
Santoso, Sentot; Wihadmadyatami, Hevi; Bakchoul, Tamam et al. (2016) Antiendothelial ?v?3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia. Arterioscler Thromb Vasc Biol 36:1517-24
Zheng, Yongwei; Adams, Tamara; Zhi, Huiying et al. (2015) Restoration of responsiveness of phospholipase C?2-deficient platelets by enforced expression of phospholipase C?1. PLoS One 10:e0119739
Zheng, Yongwei; Yu, Mei; Padmanabhan, Anand et al. (2015) Critical role of CD4 T cells in PF4/heparin antibody production in mice. Blood 125:1826-9

Showing the most recent 10 out of 229 publications