Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL045100-14
Application #
7395230
Study Section
Special Emphasis Panel (ZHL1-PPG-D (M2))
Project Start
2006-07-01
Project End
2008-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
14
Fiscal Year
2006
Total Cost
$361,906
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Wittchen, Erika S; Aghajanian, Amir; Burridge, Keith (2011) Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions. Small GTPases 2:65-76
Demorest, Zachary L; MacDuff, Donna A; Brown, William L et al. (2010) The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination. PLoS One 5:e11660
Casiraghi, Monica; Tatreau, Jason R; Abano, John B et al. (2009) In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation. J Thorac Cardiovasc Surg 138:760-7
Monaghan-Benson, Elizabeth; Burridge, Keith (2009) The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem 284:25602-11
Zanotti, Giorgio; Casiraghi, Monica; Abano, John B et al. (2009) Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. Am J Physiol Lung Cell Mol Physiol 297:L52-63
Wittchen, Erika S (2009) Endothelial signaling in paracellular and transcellular leukocyte transmigration. Front Biosci (Landmark Ed) 14:2522-45
Sallee, Jennifer L; Burridge, Keith (2009) Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells. J Biol Chem 284:14997-5006
Wang, Z; Holly, S P; Larson, M K et al. (2009) Rap1b is critical for glycoprotein VI-mediated but not ADP receptor-mediated alpha2beta1 activation. J Thromb Haemost 7:693-700
Aghajanian, Amir; Wittchen, Erika S; Campbell, Sharon L et al. (2009) Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. PLoS One 4:e8045
Denofrio, Jan C; Yuan, Weiping; Temple, Brenda R et al. (2008) Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members. Thromb Haemost 100:847-56

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