Abstract

This Core provides computer, electronics, instrumentation and machine shop support services to the Program Project Gram Investigators. The services are an essemial part of the Projects' protocol design, animal maintenance, data acquisition and data analyses. Specific services range from creating instrumentation for acute and chronic animal experimemation to managing a World Wide Web server, to precision machining of custom mechanical parts. The personnel in this core are responsible for developing and implementing advances in microcomputer technology and software, and for developing new instrumentation to meet the research needs of the Program Project. Instrumentation and computer technologies developed by the various investigators are made available to all members of the Program Project team. Imaging support for immunohistochemical, densitometic, morphometric, and stereological analyses has been added by the Core during the previous grant period by the various projects as required for their experimental protocols. The Core will continue to increase the support for histological and immunohistochemical analyses during the next funding period. The Core will continue to support the development and use of mathematical modeling to as a quantitative way to test new and integrative physiological concepts.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL051971-13
Application #
7163819
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
13
Fiscal Year
2006
Total Cost
$134,005
Indirect Cost

  Institution

Name
University of Mississippi Medical Center
Department
Type
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216

  Publications

Meschiari, Cesar A; Jung, Mira; Iyer, Rugmani Padmanabhan et al. (2018) Macrophage overexpression of matrix metalloproteinase-9 in aged mice improves diastolic physiology and cardiac wound healing after myocardial infarction. Am J Physiol Heart Circ Physiol 314:H224-H235
Hinds Jr, Terry D; Stec, David E (2018) Bilirubin, a Cardiometabolic Signaling Molecule. Hypertension 72:788-795
Adeosun, Samuel O; Moore, Kyle H; Lang, David M et al. (2018) A Novel Fluorescence-Based Assay for the Measurement of Biliverdin Reductase Activity. React Oxyg Species (Apex) 5:35-45
Hall, Michael E; Jordan, Jennifer H; Juncos, Luis A et al. (2018) BOLD magnetic resonance imaging in nephrology. Int J Nephrol Renovasc Dis 11:103-112
Bakrania, Bhavisha A; Spradley, Frank T; Satchell, Simon C et al. (2018) Heme oxygenase-1 is a potent inhibitor of placental ischemia-mediated endothelin-1 production in cultured human glomerular endothelial cells. Am J Physiol Regul Integr Comp Physiol 314:R427-R432
Chade, Alejandro R; Williams, Maxx L; Guise, Erika et al. (2018) Systemic biopolymer-delivered vascular endothelial growth factor promotes therapeutic angiogenesis in experimental renovascular disease. Kidney Int 93:842-854
Clemmer, John S; Hester, Robert L; Pruett, W Andrew (2018) Simulating a virtual population's sensitivity to salt and uninephrectomy. Interface Focus 8:20160134
Granger, Joey P; Spradley, Frank T; Bakrania, Bhavisha A (2018) The Endothelin System: A Critical Player in the Pathophysiology of Preeclampsia. Curr Hypertens Rep 20:32
da Silva, Alexandre A; Freeman, J Nathan; Hall, John E et al. (2018) Control of appetite, blood glucose, and blood pressure during melanocortin-4 receptor activation in normoglycemic and diabetic NPY-deficient mice. Am J Physiol Regul Integr Comp Physiol 314:R533-R539
Reckelhoff, Jane F; Alexander, Barbara T (2018) Reproducibility in animal models of hypertension: a difficult problem. Biol Sex Differ 9:53

Showing the most recent 10 out of 767 publications