Core A: Administrative SupportThe most critical aspect of administrative support is oversight of the science in the component projects. Dr.Robertson, Principal investigator, will meet with project leaders at least monthly on an individual bases toreview progress and to plan further research strategies, particularly emphasizing areas in which advances inone project may lead to the formulation of new hypotheses, or otherwise alter the conduct of studies in adifferent programmatic area. Dr. Robertson will be accompanied at these meetings by the PPGbiostatistician, Dr. William Dupont.Biostatistical support is a critical component of any clinical study. In view of the intensity of such patient-oriented investigations in this program project grant proposal, Dr. William Dupont, of the Division ofBiostatistics, has served all components of this proposal as a consultant and collaborator, functions that willcontinue throughout the duration of the program. Support for Dr. Dupont is therefore budgeted in this core.Investigators in this Program will be supported by the administrative services of this Core, particularly inpreparation of non-competing renewals, in financial management, and in organization of the annual mini-sitevisits of the Advisory Committees.Several investigators in the Program devote effort to more than one Project or Core, so Other Supportservices, such as telephone, medical illustrations, and reprint charges as well as Travel are budgetedcentrally here.The administrative core will be responsible for coordinating the office management of the PPG. Amy Sheltonand Glenna Osborn, efficient administrative officers, are housed in the Division of Pharmacology in MedicalResearch Building 1, where grant management for most of the PPG participants is normally handled.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL056693-11
Application #
7252848
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2007-08-01
Project End
2012-04-30
Budget Start
2007-08-01
Budget End
2008-04-30
Support Year
11
Fiscal Year
2007
Total Cost
$119,787
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Chaugai, Sandip; Dickson, Alyson L; Shuey, Megan M et al. (2018) Co-Prescription of Strong CYP1A2 Inhibitors and the Risk of Tizanidine-Associated Hypotension: A Retrospective Cohort Study. Clin Pharmacol Ther :
van den Berg, Maarten P; Almomani, Rowida; Biaggioni, Italo et al. (2018) Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome. Circ Res 122:846-854
Mar, Philip L; Raj, Satish R (2018) Orthostatic hypotension for the cardiologist. Curr Opin Cardiol 33:66-72
Mai, Tu H; Garland, Emily M; Diedrich, André et al. (2017) Hepatic and renal mechanisms underlying the osmopressor response. Auton Neurosci 203:58-66
Kawai, V K; Levinson, R T; Adefurin, A et al. (2017) A genetic risk score that includes common type 2 diabetes risk variants is associated with gestational diabetes. Clin Endocrinol (Oxf) 87:149-155
Pezawas, Thomas; Diedrich, André; Robertson, David et al. (2017) Risk of arrhythmic death in ischemic heart disease: a prospective, controlled, observer-blind risk stratification over 10 years. Eur J Clin Invest 47:231-240
Adefurin, A; Ghimire, L V; Kohli, U et al. (2017) Genetic variation in the alpha1B-adrenergic receptor and vascular response. Pharmacogenomics J 17:366-371
Kaufman, Melissa R; Chang-Kit, Laura; Raj, Satish R et al. (2017) Overactive bladder and autonomic dysfunction: Lower urinary tract symptoms in females with postural tachycardia syndrome. Neurourol Urodyn 36:610-613
Shaw, Brett H; Garland, Emily M; Black, Bonnie K et al. (2017) Optimal diagnostic thresholds for diagnosis of orthostatic hypotension with a 'sit-to-stand test'. J Hypertens 35:1019-1025
Kawai, Vivian K; Levinson, Rebecca T; Adefurin, Abiodun et al. (2017) Variation in the ?2A-adrenergic receptor gene and risk of gestational diabetes. Pharmacogenomics 18:1381-1386

Showing the most recent 10 out of 315 publications