The Histopathology and Microbiology Core (Core B) is dedicated to serving Projects 1-4 of this Program Project Grant in regard to analysis of human and animal samples. This core will ensure the quality control of sample analysis and testing throughout the Program Project Grant. The specific objectives of Core B are: 1. Evaluation of general (non-neurogenic) airway inflammation in human airway and/or mouse lung samples 2. Evaluation of neurogenic inflammation in human airway and/or mouse lung samples 3. Evaluation of airway remodeling in human airway and/or mouse lung samples 4. Quantitative M. pneumoniae culture and PCR in human airway and mouse lung samples 5. Measurement of serum IgE and IgG levels in murine models 6. Transmission electron microscopy of M. pneumoniae treated with surfactant protein-A (SP-A) Thus, Core B will be an integral part of the Program Project Grant and in doing so will have the projects function at a high standard.
| Numata, Mari; Kandasamy, Pitchaimani; Nagashima, Yoji et al. (2015) Phosphatidylinositol inhibits respiratory syncytial virus infection. J Lipid Res 56:578-87 |
| Deshane, Jessy S; Redden, David T; Zeng, Meiqin et al. (2015) Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease. J Allergy Clin Immunol 135:413-424.e15 |
| Numata, Mari; Nagashima, Yoji; Moore, Martin L et al. (2013) Phosphatidylglycerol provides short-term prophylaxis against respiratory syncytial virus infection. J Lipid Res 54:2133-43 |
| Numata, Mari; Kandasamy, Pitchaimani; Nagashima, Yoji et al. (2012) Phosphatidylglycerol suppresses influenza A virus infection. Am J Respir Cell Mol Biol 46:479-87 |
| Lugogo, Njira L; Bappanad, Divya; Kraft, Monica (2011) Obesity, metabolic dysregulation and oxidative stress in asthma. Biochim Biophys Acta 1810:1120-6 |
| Nabe, Takeshi; Hosokawa, Fusa; Matsuya, Kouki et al. (2011) Important role of neutrophils in the late asthmatic response in mice. Life Sci 88:1127-35 |
| Kandasamy, Pitchaimani; Zarini, Simona; Chan, Edward D et al. (2011) Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages. J Biol Chem 286:7841-53 |
| Wang, Ying; Voelker, Dennis R; Lugogo, Njira L et al. (2011) Surfactant protein A is defective in abrogating inflammation in asthma. Am J Physiol Lung Cell Mol Physiol 301:L598-606 |
| Anderson, John T; Zeng, Meiqin; Li, Qian et al. (2011) Elevated levels of NO are localized to distal airways in asthma. Free Radic Biol Med 50:1679-88 |
| Deshane, J; Zmijewski, J W; Luther, R et al. (2011) Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol 4:503-18 |
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