Abstract

The Administrative Core will provide administrative services for the PPG. Core A will deal with the daily management of the Program Project and will be the liaison with the Administrative Office of BU and with the Heart Lung and Blood Institute of the NIH.Dr. Morgan will contribute 5% of her time and will be assisted by an administrative assistant, Ms. Jean Daley at a time commitment of 10%. Ms. Daley will coordinate the preparation of fiscal and scientific reports, monitor monthly fund reports and facilitate communication with BU Administration as well as BBRI and U. Penn. Administration. She will also facilitate communication with the NHLBI. Core A will also organize all program activities including Work-in-Progress Meetings, the Cytoskeleton Journal Club, the Cytoskeletal Seminar Series and the Annual Retreat, which including the yearly Annual Review by the External Advisory Committee.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL086655-04
Application #
8079498
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
4
Fiscal Year
2010
Total Cost
$35,872
Indirect Cost

  Institution

Name
Boston University
Department
Type
DUNS #
049435266
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Guo, Ming; Pegoraro, Adrian F; Mao, Angelo et al. (2017) Cell volume change through water efflux impacts cell stiffness and stem cell fate. Proc Natl Acad Sci U S A 114:E8618-E8627
Espinoza-Fonseca, L Michel; Alamo, Lorenzo; Pinto, Antonio et al. (2015) Sequential myosin phosphorylation activates tarantula thick filament via a disorder-order transition. Mol Biosyst 11:2167-79
Schmidt, William M; Lehman, William; Moore, Jeffrey R (2015) Direct observation of tropomyosin binding to actin filaments. Cytoskeleton (Hoboken) 72:292-303
Alamo, Lorenzo; Li, Xiaochuan Edward; Espinoza-Fonseca, L Michel et al. (2015) Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back. Mol Biosyst 11:2180-9
Saphirstein, Robert J; Gao, Yuan Z; Lin, Qian Qian et al. (2015) Cortical actin regulation modulates vascular contractility and compliance in veins. J Physiol 593:3929-41
Begonja, Antonija Jurak; Pluthero, Fred G; Suphamungmee, Worawit et al. (2015) FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. Blood 126:80-8
Yang, Shixin; Barbu-Tudoran, Lucian; Orzechowski, Marek et al. (2014) Three-dimensional organization of troponin on cardiac muscle thin filaments in the relaxed state. Biophys J 106:855-64
Guo, Ming; Ehrlicher, Allen J; Jensen, Mikkel H et al. (2014) Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy. Cell 158:822-832
Morgan, Kathleen G (2014) The importance of the smooth muscle cytoskeleton to preterm labour. Exp Physiol 99:525-9
Lehman, William; Li, Xiaochuan Edward; Orzechowski, Marek et al. (2014) The structural dynamics of ?-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules. Arch Biochem Biophys 552-553:68-73

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