Abstract

2). 5. Generation of tagged cDNA expression constructs for testing antibody specificity (all Projects). 6. Provision of viral gene targeting constructs (Proiects 1. 2, and 4). II. Tissue culture services 1. Culture and transfection of cell lines to test immunoreagent specificity (all Projects). 2. Regional tissue harvesting for molecular and biochemical analysis (Proiects 1. 2. and 4). 3. Isolation of brain microvessels (Proiect 4). III. Biochemical services 1. Analysis of reactive oxygen species (ROS) production in animal tissue (Proiects 1. 3. and 4). 2. Determination of NADPH Oxidase activity in animal tissue (

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL096571-03
Application #
8299979
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
3
Fiscal Year
2011
Total Cost
$215,375
Indirect Cost

  Institution

Name
Weill Medical College of Cornell University
Department
Type
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

McAlinn, Helena R; Reich, Batsheva; Contoreggi, Natalina H et al. (2018) Sex Differences in the Subcellular Distribution of Corticotropin-Releasing Factor Receptor 1 in the Rat Hippocampus following Chronic Immobilization Stress. Neuroscience 383:98-113
Ma, Qian; Yang, Jianmin; Milner, Teresa A et al. (2017) SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease. JCI Insight 2:
McEwen, Bruce S; Milner, Teresa A (2017) Understanding the broad influence of sex hormones and sex differences in the brain. J Neurosci Res 95:24-39
Cole, Daniel C; Chung, Youngcheul; Gagnidze, Khatuna et al. (2017) Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology. Proc Natl Acad Sci U S A 114:13272-13277
Marques-Lopes, Jose; Tesfaye, Ephrath; Israilov, Sigal et al. (2017) Redistribution of NMDA Receptors in Estrogen-Receptor-?-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure. Neuroendocrinology 104:239-256
Almey, Anne; Milner, Teresa A; Brake, Wayne G (2016) Estrogen receptor ? and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum. Neurosci Lett 622:118-23
Faraco, Giuseppe; Park, Laibaik; Zhou, Ping et al. (2016) Hypertension enhances A?-induced neurovascular dysfunction, promotes ?-secretase activity, and leads to amyloidogenic processing of APP. J Cereb Blood Flow Metab 36:241-52
Mazid, Sanoara; Hall, Baila S; Odell, Shannon C et al. (2016) Sex differences in subcellular distribution of delta opioid receptors in the rat hippocampus in response to acute and chronic stress. Neurobiol Stress 5:37-53
Mende, Michael; Fletcher, Emily V; Belluardo, Josephine L et al. (2016) Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron 90:1189-1202
Harward, Stephen C; Hedrick, Nathan G; Hall, Charles E et al. (2016) Autocrine BDNF-TrkB signalling within a single dendritic spine. Nature 538:99-103

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