Abstract

CA, WEBB The Administrative Core will promote networking and exchange between all components of the Program Project. It will identify elements within projects where collaborations can be established to synergize outcomes and intellect. It will disseminate information on current research trends in hypertension and information about regional, national and international meetings. Dr. Webb will be the leader of Core A and supported by Dr. Brands. Both investigators have over 25 years of experience in hypertension research and Program Project management. The Administrative Core has three major responsibilities. The first is to facilitate the various administrative aspects associated with the Program Project: record keeping, scheduling, financial bookkeeping, progress reports, manuscripts, etc. The second is to foster scientific progress and coordination, both between different projects and between program investigators and scientists outside of Georgia Regents University. Finally, the Administrative Core will provide biostatistical and computing resources for each of the projects in the program.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL134604-02
Application #
9415060
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Program Officer
Maric-Bilkan, Christine
Project Start
Project End
Budget Start
2018-02-01
Budget End
2019-01-31
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
Augusta University
Department
Type
DUNS #
City
Augusta
State
GA
Country
United States
Zip Code
30912

  Publications

Wenceslau, Camilla F; McCarthy, Cameron G; Webb, R Clinton (2018) To Be, or Nox to Be, Endoplasmic Reticulum Stress in Hypertension. Hypertension 72:59-60
McCarthy, Cameron G; Wenceslau, Camilla F (2018) Adopting an Orphan: How Could GRP35 Contribute to Angiotensin II-Dependent Hypertension? Am J Hypertens 31:973-975
Bressan, Alecsander F; Fonseca, Gisele A; Tostes, Rita C et al. (2018) Interleukin-10 negatively modulates extracellular signal-regulated kinases 1 and 2 in aorta from hypertensive mouse induced by angiotensin II infusion. Fundam Clin Pharmacol :
Abdul, Yasir; Abdelsaid, Mohammed; Li, Weiguo et al. (2018) Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4. Mol Neurobiol :
Ray, Sarah C; Baban, Babak; Tucker, Matthew A et al. (2018) Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells. J Immunol 200:3568-3586
McCarthy, Cameron G; Wenceslau, Camilla F; Ogbi, Safia et al. (2018) Toll-Like Receptor 9-Dependent AMPK? Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells. J Pharmacol Exp Ther 365:60-71
Martinez-Quinones, Patricia; McCarthy, Cameron G; Watts, Stephanie W et al. (2018) Hypertension Induced Morphological and Physiological Changes in Cells of the Arterial Wall. Am J Hypertens 31:1067-1078
Komic, Amel; Martinez-Quinones, Patricia; McCarthy, Cameron G et al. (2018) Increase in soluble protein oligomers triggers the innate immune system promoting inflammation and vascular dysfunction in the pathogenesis of sepsis. Clin Sci (Lond) 132:1433-1438
Gonçalves, Tiago Tomazini; Lazaro, Carolina M; De Mateo, Fernanda G et al. (2018) Effects of glucosyl-hesperidin and physical training on body weight, plasma lipids, oxidative status and vascular reactivity of rats fed with high-fat diet. Diabetes Metab Syndr Obes 11:321-332
Wynne, Brandi M; McCarthy, Cameron G; Szasz, Theodora et al. (2018) Protein kinase C? deletion causes hypotension and decreased vascular contractility. J Hypertens 36:510-519

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