Because diabetes is a chronic condition with substantial associated morbidity among minority elders and is a condition in which self- management is particularly crucial in the prevention of complications, we set out to implement and evaluate culturally tailored patient-centered intervention to improve glycemic control by improving patient knowledge, self-management skills, and empowerment among community-residing minority older adults with diabetes.
Specific aims of the project are: 1) to determine whether a multidimensional, culturally tailored intervention that focuses on increasing knowledge about diabetes care, empowerment, and self-management skills, will lead to better glycemic, lipid blood pressure, and weight control, fewer acute diabetes- related symptoms, and improvements in health-related quality of life; 2) to determine whether this intervention will lead to improvements in process of care; 3) to determine the cost-effectiveness of the intervention when compared to usual care. To evaluate the effectiveness of the intervention, the research team will conduct a controlled clinical trial that will randomize 600 older African American and Latino persons with diabetes who are cared for in 6 public clinics affiliated with the Martin Luther King-Drew University Medical Center. Randomization will occur at the patient level. The primary endpoint for the trial will be differences in glycemic control as reflected by mean difference in hemoglobin A1c over time for the active intervention versus usual care control group. The trial will also track a number of important secondary endpoints both before and after exposed to the intervention: self-management skills, knowledge about diabetes, diabetes-specific symptoms, quality of life, low density lipoprotein levels, blood pressure, weight, quality of care, and health care service use. The study will also collect data on variables that are likely to modify the effectiveness of the intervention, such as acculturation, insurance status and benefit structure, and social support. These data will provide the needed information to evaluate both the effectiveness and the cost effectiveness of the intervention among older African Americans and Latinos with diabetes. Because the effectiveness and specific design of the intervention is likely to be influenced by cultural factors, the cultural factors, the clinical trial will be powered for pre-planned sub-group analyses among African Americans and Latinos. The content of the proposed intervention will be determined by the result of a funded pilot study that is currently designing the intervention and assessing whether it is acceptable and feasible for African American and Latino older persons with diabetes. In summary, by designing and testing the intervention and assessing whether it is acceptable and feasible for African American and Latino older persons with diabetes. In summary, by designing and testing an intervention that focuses on the patient rather than the system of care, we hope to arm older diabetes with the needed skills, knowledge, and empowerment to have the best possible glycemic control and process of health care regardless of the resources available in their care setting.

Agency
National Institute of Health (NIH)
Institute
Agency for Healthcare Research and Quality (AHRQ)
Type
Research Program Projects (P01)
Project #
5P01HS010858-03
Application #
6661552
Study Section
Special Emphasis Panel (ZHS1)
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
3
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Calderón, José Luis; Bazargan, Mohsen; Sangasubana, Nisaratana et al. (2010) A comparison of two educational methods on immigrant Latinas breast cancer knowledge and screening behaviors. J Health Care Poor Underserved 21:76-90
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Rumptz, Maureen H; Tobias, Carol; Rajabiun, Serena et al. (2007) Factors associated with engaging socially marginalized HIV-positive persons in primary care. AIDS Patient Care STDS 21 Suppl 1:S30-9
Calderon, Jose L; Baker, Richard S; Fabrega, Horacio et al. (2006) An ethno-medical perspective on research participation: a qualitative pilot study. MedGenMed 8:23
Wong, Mitchell D; Tagawa, Tomoko; Hsieh, Hsin-Ju et al. (2005) Differences in cause-specific mortality between Latino and white adults. Med Care 43:1058-62
Calderon, Jose L; Shaheen, Magda; Pan, Deyu et al. (2005) Multi-cultural surveillance for ectopic pregnancy: California 1991-2000. Ethn Dis 15:S5-20-4
Morales, Leo S; Staiger, Douglas; Horbar, Jeffrey D et al. (2005) Mortality among very low-birthweight infants in hospitals serving minority populations. Am J Public Health 95:2206-12
Rogowski, Jeannette A; Staiger, Douglas O; Horbar, Jeffrey D (2004) Variations in the quality of care for very-low-birthweight infants: implications for policy. Health Aff (Millwood) 23:88-97
Calderon, Jose Luis; Zadshir, Ashraf; Norris, Keith (2004) A survey of kidney disease and risk-factor information on the World Wide Web. MedGenMed 6:3
Calderon, Jose Luis; Zadshir, Ashraf; Norris, Keith (2004) Structure and content of chronic kidney disease information on the World Wide Web: barriers to public understanding of a pandemic. Nephrol News Issues 18:76, 78-9, 81-4

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