Abstract

The transgenic core will have responsibility for helping laboratories work effectively with existing strains of transgenic mice, generate new strains of transgenic mice, and prepare chimeric animals for analyses of brain function. This core will maintain colonies of mice adequate for generating such animals, will generate and characterize lines of embryonic stem cells, help prepare mice with altered or mutated genes by homologous recombination, help prepare homozygous mutant embryonic stem cells for use in generating chimeric mice, and educate postdoctoral fellows and students in these techniques.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS016033-20
Application #
6359665
Study Section
Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
20
Fiscal Year
2000
Total Cost
$148,221
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Chen, Albert I; Zang, Keling; Masliah, Eliezer et al. (2016) Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum. Sci Rep 6:20201
Nicoll, Roger A; Roche, Katherine W (2013) Long-term potentiation: peeling the onion. Neuropharmacology 74:18-22
Herring, Bruce E; Shi, Yun; Suh, Young Ho et al. (2013) Cornichon proteins determine the subunit composition of synaptic AMPA receptors. Neuron 77:1083-96
Vigers, A J; Amin, D S; Talley-Farnham, T et al. (2012) Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior. Neuroscience 212:1-18
Sanchez-Ortiz, Efrain; Yui, Daishi; Song, Dongli et al. (2012) TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. J Neurosci 32:4065-79
Baydyuk, Maryna; Russell, Theron; Liao, Guey-Ying et al. (2011) TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons. Proc Natl Acad Sci U S A 108:1669-74
Chen, Albert I; Nguyen, Cindy N; Copenhagen, David R et al. (2011) TrkB (tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex. J Neurosci 31:2769-80
Blankenship, Aaron G; Ford, Kevin J; Johnson, Juliette et al. (2009) Synaptic and extrasynaptic factors governing glutamatergic retinal waves. Neuron 62:230-41
Arikkath, Jyothi; Peng, I-Feng; Ng, Yu Gie et al. (2009) Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development. J Neurosci 29:5435-42
Arikkath, Jyothi; Reichardt, Louis F (2008) Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity. Trends Neurosci 31:487-94

Showing the most recent 10 out of 65 publications