Abstract

The objective of the proposed research is to characterize structure- function relationships underlying auditory pattern perception. The experimental approach is designed to divulge functional dissociations in methods of neurology, cognitive psychology, and audiology are applied to the examination of patients with differential lateralization and localization of dissociable functions within the auditory cortex and related heteromodal areas. These data will provide an empirical basis by which to construct and test computational models of neural networks in auditory pattern perception. The working hypothesis are: 1) injury to the auditory cortex disrupts modality-specific associative functions which abstract constancies in frequency patterns and integrate spectral information over time; 2) acoustic -discriminative and semantic-associative functions in auditory information processing are differentially distributed within the right and left hemispheres.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS017778-12
Application #
3782804
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Shimamura, Arthur P; Marian, Diane E; Haskins, Andrew L (2013) Neural correlates of emotional regulation while viewing films. Brain Imaging Behav 7:77-84
Shimamura, Arthur P (2010) Hierarchical relational binding in the medial temporal lobe: the strong get stronger. Hippocampus 20:1206-16
Shimamura, Arthur P; Wickens, Thomas D (2009) Superadditive memory strength for item and source recognition: the role of hierarchical relational binding in the medial temporal lobe. Psychol Rev 116:1-19
Miller, Michael B; Donovan, Christa-Lynn; Van Horn, John D et al. (2009) Unique and persistent individual patterns of brain activity across different memory retrieval tasks. Neuroimage 48:625-35
Mullette-Gillman, O'Dhaniel A; Cohen, Yale E; Groh, Jennifer M (2009) Motor-related signals in the intraparietal cortex encode locations in a hybrid, rather than eye-centered reference frame. Cereb Cortex 19:1761-75
Turken, Andu; Whitfield-Gabrieli, Susan; Bammer, Roland et al. (2008) Cognitive processing speed and the structure of white matter pathways: convergent evidence from normal variation and lesion studies. Neuroimage 42:1032-44
Saygin, Ayse Pinar; Wilson, Stephen M; Dronkers, Nina F et al. (2004) Action comprehension in aphasia: linguistic and non-linguistic deficits and their lesion correlates. Neuropsychologia 42:1788-804
Bates, Elizabeth; Wilson, Stephen M; Saygin, Ayse Pinar et al. (2003) Voxel-based lesion-symptom mapping. Nat Neurosci 6:448-50
Stone, Valerie E; Cosmides, Leda; Tooby, John et al. (2002) Selective impairment of reasoning about social exchange in a patient with bilateral limbic system damage. Proc Natl Acad Sci U S A 99:11531-6
Eliassen, J C; Baynes, K; Gazzaniga, M S (2000) Anterior and posterior callosal contributions to simultaneous bimanual movements of the hands and fingers. Brain 123 Pt 12:2501-11

Showing the most recent 10 out of 45 publications