The Neuropsychological Core will provide neurobahavioral assessment techniques to the Center. These methods will included Core Neuropsychology Battery, measures of functional competence and of skill relevant to activities of daily living, automated tests for assessing and effects of sedating agents, dementia screening tests, and methods for measuring psychopathology in the elderly. The developmental work of the Core will focus on two activities. One involves assessing the reliability of quantitative 31P NMR measures obtained when different NMR technicians perform shimming and NMR techniques perform shimming and NMIR techniques perform shimming and phasing. The other activity involves developing behavioral activation techniques to alter regional cerebral blood flow measured by NMR methods. The Neuropsychology Core will be providing support to Projects 1, 3 and 4. It will also collaborate with the NMR and Biostatistics Cores on the quality control of NMR measurcs.

Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Henry Ford Health System
Department
Type
DUNS #
073134603
City
Detroit
State
MI
Country
United States
Zip Code
48202
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Zhang, Rui Lan; Zhang, Zheng Gang; Chopp, Michael (2013) Targeting nitric oxide in the subacute restorative treatment of ischemic stroke. Expert Opin Investig Drugs 22:843-51
Yan, Tao; Chopp, Michael; Ning, Ruizhuo et al. (2013) Intracranial aneurysm formation in type-one diabetes rats. PLoS One 8:e67949
Hernández-Vázquez, A; Wolf, B; Pindolia, K et al. (2013) Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder. Mol Genet Metab 110:248-54
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Wang, Shiyang; Chopp, Michael; Nazem-Zadeh, Mohammad-Reza et al. (2013) Comparison of neurite density measured by MRI and histology after TBI. PLoS One 8:e63511
Santra, Manoranjan; Chopp, Michael; Zhang, Zheng Gang et al. (2012) Thymosin ? 4 mediates oligodendrocyte differentiation by upregulating p38 MAPK. Glia 60:1826-38

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