Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
3P01NS030619-04S1
Application #
2268596
Study Section
Neurological Disorders Program Project Review A Committee (NSPA)
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Surgery
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
van den Pol, A N; Spencer, D D (2000) Differential neurite growth on astrocyte substrates: interspecies facilitation in green fluorescent protein-transfected rat and human neurons. Neuroscience 95:603-16
Jiang, W; Duong, T M; de Lanerolle, N C (1999) The neuropathology of hyperthermic seizures in the rat. Epilepsia 40:5-19
Telfeian, A E; Spencer, D D; Williamson, A (1999) Lack of correlation between neuronal hyperexcitability and electrocorticographic responsiveness in epileptogenic human neocortex. J Neurosurg 90:939-45
O'Connor, E R; Sontheimer, H; Spencer, D D et al. (1998) Astrocytes from human hippocampal epileptogenic foci exhibit action potential-like responses. Epilepsia 39:347-54
de Lanerolle, N C; Eid, T; von Campe, G et al. (1998) Glutamate receptor subunits GluR1 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus. Eur J Neurosci 10:1687-703
Haak, L L; Heller, H C; van den Pol, A N (1997) Metabotropic glutamate receptor activation modulates kainate and serotonin calcium response in astrocytes. J Neurosci 17:1825-37
von Campe, G; Spencer, D D; de Lanerolle, N C (1997) Morphology of dentate granule cells in the human epileptogenic hippocampus. Hippocampus 7:472-88
Brines, M L; Sundaresan, S; Spencer, D D et al. (1997) Quantitative autoradiographic analysis of ionotropic glutamate receptor subtypes in human temporal lobe epilepsy: up-regulation in reorganized epileptogenic hippocampus. Eur J Neurosci 9:2035-44
de Lanerolle, N C; Williamson, A; Meredith, C et al. (1997) Dynorphin and the kappa 1 ligand [3H]U69,593 binding in the human epileptogenic hippocampus. Epilepsy Res 28:189-205
Van Den Pol, A N; Obrietan, K; Belousov, A (1996) Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture. Neuroscience 74:653-74

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