The purpose of this Core is to make available transgenic and knockout mutants for Projects 1 and 3 of the program. One particular strength of this Transgenic Animal Core is that Dr. Chan (Core Leader) will provide his expertise in the use of superoxide dismutase, transgenic and knockout mutant mice, as well as oxygen radical-related biochemistry and molecular biology to the other projects, including 1 and 3. In addition, this Core will provide our expertise in molecular analysis of gene expression (PCR, RT-PCR) and gel electrophoresis for enzyme activities of CuZnSOD and MnSOD in mice and rats. Thus, this Transgenic Animal Core provides a unique vehicle for the projects to achieve their research goals with various transgenic and knockout animals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS037520-03
Application #
6480801
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
2001-03-01
Project End
2002-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2001
Total Cost
$155,764
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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