The Data Acquisition and Analysis Core is both a service and development core that will support the dataacquisition and analysis needs of all investigators. By consolidating support resources into this Core, we willachieve efficiencies in data acquisition and analysis and economies of scale that will enable us to increaseour PPG from five to nine faculty investigators and to greatly expand our scientific scope. The DataAcquisition and Analysis Core has five major Aims.
The first Aim i s to provide direct services to allinvestigators within this Program Project Grant (PPG). These services include (1) a service for recruiting,screening, and scheduling all experimental subjects forfMRI experiments, (2) the provision of a PPGdedicatedexperimenter to supervise and run all experimental sessions (in addition to the certified MRtechnologist provided by the Brain Imaging and Analysis Center to acquire images for all studies), (3) theprovision of a PPG-dedicated data analyst who will assess the quality of all MRI data using purpose-builtsoftware tools, and who will guide all fMRI data through all preprocessing steps of the image analysispipeline.
The second Aim i s to support the acquisition of all intracranial event-related potential (ERP) studiesperformed at Yale University for all PPG investigators.
The third Aim i s to maintain all visual and auditorystimulus delivery systems, response manipulanda, eye trackers, experimental control computers, andexperimental control software.
The fourth Aim i s to leverage the BIAC's participation in the NIH/NCRR'sBioinformatics Research Network (BIRN) consortium so that all software tools developed by BIRN scientistsand software engineers are integrated into the PPG's data analysis pipeline. The fifth Aim is to develop asemi-automated system based for data documentation and data provenance that incorporates principlesfrom the FDA's 'Good Clinical Practices' guidelines.
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