Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
1P01NS050315-01A2
Application #
7192209
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2007-04-24
Budget End
2007-12-31
Support Year
1
Fiscal Year
2007
Total Cost
$285,980
Indirect Cost
Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
Thrane, Alexander S; Rangroo Thrane, Vinita; Nedergaard, Maiken (2014) Drowning stars: reassessing the role of astrocytes in brain edema. Trends Neurosci 37:620-8
Rangroo Thrane, Vinita; Thrane, Alexander S; Wang, Fushun et al. (2013) Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering. Nat Med 19:1643-8
Verkhratsky, Alexei; Sofroniew, Michael V; Messing, Albee et al. (2012) Neurological diseases as primary gliopathies: a reassessment of neurocentrism. ASN Neuro 4:
Fujita, Takumi; Williams, Erika K; Jensen, Tina K et al. (2012) Cultured astrocytes do not release adenosine during hypoxic conditions. J Cereb Blood Flow Metab 32:e1-7
Nedergaard, Maiken; Verkhratsky, Alexei (2012) Artifact versus reality--how astrocytes contribute to synaptic events. Glia 60:1013-23
Oberheim, Nancy Ann; Goldman, Steven A; Nedergaard, Maiken (2012) Heterogeneity of astrocytic form and function. Methods Mol Biol 814:23-45
Rangroo Thrane, V; Thrane, A S; Chang, J et al. (2012) Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy. Neuroscience 220:247-55
Rita, Giuliano; Emily, Terho; Rempe, David A (2012) Cocultures of neurons and astrocytes as a model for examining hypoxia-induced neuronal death. Methods Mol Biol 814:353-66
McClain, Crystal R; Sim, Fraser J; Goldman, Steven A (2012) Pleiotrophin suppression of receptor protein tyrosine phosphatase-?/? maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells. J Neurosci 32:15066-75
Sim, Fraser J; McClain, Crystal R; Schanz, Steven J et al. (2011) CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells. Nat Biotechnol 29:934-41

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