Training and Education Program - Abstract Increasing diversity in biomedical research workforce to improve the Nation's capacity to address and eliminate health disparities is a critical need recognized nationwide. The objective of this project is to perform feasibility study in enhancement of cancer research training and education for Howard students through the partnership of Howard University and Johns Hopkins Cancer Center. The hypothesis is that building high quality and sustainable collaborative cancer research training and education program at HBCU institutes can accelerate the improvement of number and quality of minority biomedical investigators. The design of this program is based on the overall priorities of the P20 application. Thereby, this feasibility study of cancer research training and education program will have a special emphasis on HPV- associated cancers and cancer health disparities.
Our specific aims are: 1) To establish an effective and sustainable mentoring network between the Johns Hopkins Medical Institutes and Howard University to support a minority initiative in cancer research 2) To provide short-term cancer research training experience opportunities for Howard students interested in biomedical and behavioral health sciences to foster long-term career opportunities in these fields 3) To develop and implement a new institutional curriculum for cancer education among Howard health professional faculty, residents and students, with focus on an increasing important disease of HPV related oropharyngeal cancer, and related research and applications. Our ultimate goal is to create effective, sustainable and collaborative cancer research training and education infrastructure at Howard University to increase the development of minority candidates with careers focused on cancer research, and to improve the ability of health professional students in translation of new discoveries and innovation in the laboratory to the bedside, into practice and populations, to eliminate cancer health disparity. Successfully conducting of this project will greatly help the submission and funding NCI cancer education grant and/or cancer research training grant to support and extend the cancer research training and education infrastructure at Howard University. This Award will also have a significant impact on strengthening the cancer research environment at Howard University.

Public Health Relevance

Training and Education Program - Project Narrative: This project includes feasibility studies in cancer research training and education through the partnership of Howard University and the Johns Hopkins Cancer Center leading to minority initiative. The project proposes to establish effective and sustainable mentoring network between Hopkins and Howard to support short-term cancer research training and new institutional curriculum of cancer education. The ultimate goal is to improve the number and quality of minority cancer researchers and facilitate cancer training and education in a minority serving institution.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants (P20)
Project #
5P20CA192988-02
Application #
8934346
Study Section
Special Emphasis Panel (ZCA1-PCRB-C)
Program Officer
Moten, Carmen P
Project Start
Project End
Budget Start
2015-09-01
Budget End
2016-08-31
Support Year
2
Fiscal Year
2015
Total Cost
$51,956
Indirect Cost
$19,702
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Yang, Andrew; Peng, Shiwen; Farmer, Emily et al. (2017) Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus. Cell Biosci 7:46
Peng, Shiwen; Qiu, Jin; Yang, Andrew et al. (2016) Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease. Cell Biosci 6:16
Hararah, Mohammad Khalid; Pollack, Craig Evan; Garza, Mary A et al. (2015) The Relationship Between Education and Prostate-Specific Antigen Testing Among Urban African American Medicare Beneficiaries. J Racial Ethn Health Disparities 2:176-83
Lee, Sung-Jong; Song, Liwen; Yang, Ming-Chieh et al. (2015) Local administration of granulocyte macrophage colony-stimulating factor induces local accumulation of dendritic cells and antigen-specific CD8+ T cells and enhances dendritic cell cross-presentation. Vaccine 33:1549-55
Yang, Benjamin; Yang, Andrew; Peng, Shiwen et al. (2015) Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination. Cell Biosci 5:35
Lee, Young-Ho; Bae, Hyun Cheol; Noh, Kyung Hee et al. (2015) Gain of HIF-1? under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes. Clin Cancer Res 21:1438-46
Sun, Y; Peng, S; Qiu, J et al. (2015) Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors. Gene Ther 22:528-35