overall goal of this INBRE renewal application is to continue the facilitation of quality biomedical research activities throughout the State of Louisiana with an emphasis on building research capacity and workforce development. The Louisiana Biomedical Research Network (LBRN) has established a strong foundation for interdisciplinary and interinstitutional research, education, training, and mentoring programs focused on seven primarily undergraduate institutions (PUIs). These PUIs have been chosen as partners based on their interest and their missions' fit with one or more of the three thematic areas of the LBRN: Computational Biology, Molecular Mechanisms of Disease, and Therapeutic and Preventive Medicine. Undergraduate students from seventeen other PUIs have the opportunity to participate in the research outreach program. Faculty and students at PUIs will be mentored and supported by scientists in the flagship, LSU, and five biomedical- research-intensive institutions. A leading-edge cyberinfrastructure connects all of these units. Overlaying all of our activities will be regular metric-driven assessment of all programs, including cores, using internal and external reviewers. Major changes have been made to improve the currently successful LBRN program. These include: improvement and expansion of our cyberinfrastructure; increased interaction with existing state COBREs; and the expansion of the number of PUIs from five to seven, adding one additional historically black college. We will also partner with Louisiana's new IDeA CTR (LA CaTS) to provide more translational science research experiences for PUI faculty and students. Undergraduate research experiences will be expanded to include opportunities during the academic year. As a demonstration of their recognition of the LBRNs importance to the state, the Louisiana Board of Regents has agreed to continue to provide a match of $1.14 million for the new application. Other support from universities brings this total match to more than $2.93 million. With these improvements and this match it is clear that the LBRN will meet its goals and those of the national INBRE program.

Public Health Relevance

The Louisiana Biomedical Research Network (LBRN) is a project funded by the National Institutes of Health. LBRN provides expert educational, training, and research opportunities for undergraduate students, graduate students, and faculty at Louisiana's primarily undergraduate institutions of higher education. The result of this expanded infrastructure, educational support, and linkages with the state's research-intensive universities and institutes is new research findings that impact public health and increase Louisiana's biotechnical and biomedical workforce capacity.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
3P20GM103424-15S1
Application #
9320356
Study Section
Special Emphasis Panel (ZGM1-TWD-0 (IN))
Program Officer
Arora, Krishan
Project Start
2001-09-25
Project End
2020-04-30
Budget Start
2016-05-01
Budget End
2017-04-30
Support Year
15
Fiscal Year
2016
Total Cost
$249,944
Indirect Cost
$79,441
Name
Louisiana State University A&M Col Baton Rouge
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
075050765
City
Baton Rouge
State
LA
Country
United States
Zip Code
70803
Wang, Hua; Sui, Ning; Bai, Xue et al. (2018) Emission Recovery and Stability Enhancement of Inorganic Perovskite Quantum Dots. J Phys Chem Lett 9:4166-4173
Zhang, Xiaoyu; Lu, Min; Zhang, Yu et al. (2018) PbS Capped CsPbI3 Nanocrystals for Efficient and Stable Light-Emitting Devices Using p-i-n Structures. ACS Cent Sci 4:1352-1359
Fakhruddin, Selim; Alanazi, Wael A; Alhamami, Hussain N et al. (2018) Hyperglycaemia induced by chronic i.p. and oral glucose loading leads to hypertension through increased Na+ retention in proximal tubule. Exp Physiol 103:236-249
Kaur, Gagandeep; Bagam, Prathyusha; Pinkston, Rakeysha et al. (2018) Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms. Toxicology 398-399:52-67
Al-Horani, Rami A; Afosah, Daniel K (2018) Recent advances in the discovery and development of factor XI/XIa inhibitors. Med Res Rev 38:1974-2023
Singh, Dhirendra P; Kaur, Gagandeep; Bagam, Prathyusha et al. (2018) Membrane microdomains regulate NLRP10- and NLRP12-dependent signalling in A549 cells challenged with cigarette smoke extract. Arch Toxicol 92:1767-1783
Mei, Suyu; Flemington, Erik K; Zhang, Kun (2018) Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis. BMC Genomics 19:505
Shen, Xinyu; Sun, Chun; Bai, Xue et al. (2018) Efficient and Stable CsPb(Br/I)3@Anthracene Composites for White Light-Emitting Devices. ACS Appl Mater Interfaces 10:16768-16775
Yin, Wenxu; Zhang, Xiaoyu; Bai, Xue et al. (2018) Low-Cost One-Pot Synthesis of WS2 Quantum Dots with Wide Emission Spectrum for Light-Emitting Applications. Chempluschem 83:1052-1056
Zhang, Wensheng; Flemington, Erik K; Zhang, Kun (2018) Driver gene mutations based clustering of tumors: methods and applications. Bioinformatics 34:i404-i411

Showing the most recent 10 out of 104 publications