Bioinformatics Core The Bioinformatics Core, based at the University of Louisville Health Science Campus, is designed to serve the bioinformatics needs of faculty and students within KBRIN-affiliated institutions. A specific focus is placed on DNA and RNA sequence analysis (i.e. ?Genomics? and ?Transcriptomics?), with an expertise in the field of high- throughput genomic and transcriptomic data resulting from array-based and high-throughput sequencing technologies. We have developed the core through recruitment of expert faculty and postdoctoral level research associates so as to quickly build a capacity for bioinformatics research, as well as, to provide service and collaboration with biomedical research scientists. In addition, the core provides multiple levels of student training activities. We will continue to pursue those activities that lead to excellence in this rapidly evolving scientific arena.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103436-20
Application #
9917797
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Louisville
Department
Type
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292
Gonzalez, O A; Kirakodu, S; Novak, M J et al. (2018) Comparative analysis of microbial sensing molecules in mucosal tissues with aging. Immunobiology 223:279-287
Ha, Dat Thinh; Ghosh, Sthitodhi; Ahn, Chong H et al. (2018) Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip. Analyst 143:4009-4016
Song, Ming; Li, Xiaohong; Zhang, Xiang et al. (2018) Dietary copper-fructose interactions alter gut microbial activity in male rats. Am J Physiol Gastrointest Liver Physiol 314:G119-G130
Yates, Justin R; Gunkel, Benjamin T; Rogers, Katherine K et al. (2018) Effects of N-methyl-d-aspartate receptor (NMDAr) uncompetitive antagonists in a delay discounting paradigm using a concurrent-chains procedure. Behav Brain Res 349:125-129
Carlson, Katy; Tyler, Joseph C (2018) Accents, Not Just Prosodic Boundaries, Influence Syntactic Attachment. Lang Speech 61:246-276
Weber, Gregory J; Foster, Jaleyea; Pushpakumar, Sathnur B et al. (2018) Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation. Pharmacol Res 134:157-165
Bickford, Martha E (2018) Synaptic organization of the dorsal lateral geniculate nucleus. Eur J Neurosci :
Stenslik, M J; Evans, A; Pomerleau, F et al. (2018) Methodology and effects of repeated intranasal delivery of DNSP-11 in awake Rhesus macaques. J Neurosci Methods 303:30-40
Yates, Justin R (2018) Dissecting drug effects in preclinical models of impulsive choice: emphasis on glutamatergic compounds. Psychopharmacology (Berl) 235:607-626
Klinefelter, Kelsey; Hooven, Molly Kromme; Bates, Chloe et al. (2018) Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders. Mamm Genome 29:112-127

Showing the most recent 10 out of 193 publications