? Centralized Shared Resources Core The mission of the Centralized Shared Resources (CSR) Core is to expand Delaware?s biomedical research infrastructure, capital, and capacity through the provision of centralized shared instrumentation and services, while promoting basic, clinical, and translational biomedical research and collaborating across Delaware institutions in order to achieve the overall mission of the DE-INBRE. Delaware INBRE core facilities have a long history of providing access to state-of-the-art instrumentation, advanced technologies, services, and related expertise. The instrumentation and service needs of biomedical researchers are continually changing and expanding. In response, DE-INBRE has greatly expanded its core facility network. To accommodate this network growth, a higher-level Centralized Shared Resources Core was created. Under this umbrella structure are the well-established Centralized Research Instrumentation Core (CRIC) and a newly formed Research Support Network (RSN) for providing access to expertise and support services in biostatistics, epidemiology, editorial services, data visualization, and presentation in areas related to community engagement, population, and clinical research.
Specific Aims 1. Expand the DE-INBRE network of instrumentation and service core facilities. 2. Enhance DE-INBRE core facility infrastructure through the formation of core facility hubs. 3. Broaden core facility access and engagement of research investigators. 4. Enhance core training and workforce development for students and core scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103446-20
Application #
9930651
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Delaware
Department
Type
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Bialk, Pawel; Wang, Yichen; Banas, Kelly et al. (2018) Functional Gene Knockout of NRF2 Increases Chemosensitivity of Human Lung Cancer A549 Cells In Vitro and in a Xenograft Mouse Model. Mol Ther Oncolytics 11:75-89
Bhattacharya, Moumita; Jurkovitz, Claudine; Shatkay, Hagit (2018) Chronic Kidney Disease stratification using office visit records: Handling data imbalance via hierarchical meta-classification. BMC Med Inform Decis Mak 18:125
Kao, Chen-Yuan; Papoutsakis, Eleftherios T (2018) Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and progenitor cells. Sci Adv 4:eaau6762
McAllister, Sean M; Moore, Ryan M; Chan, Clara S (2018) ZetaHunter, a Reproducible Taxonomic Classification Tool for Tracking the Ecology of the Zetaproteobacteria and Other Poorly Resolved Taxa. Microbiol Resour Announc 7:
Haider, Michael J; Zhang, Huixi Violet; Sinha, Nairiti et al. (2018) Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles. Soft Matter 14:5488-5496
McIlvain, Grace; Schwarb, Hillary; Cohen, Neal J et al. (2018) Mechanical properties of the in vivo adolescent human brain. Dev Cogn Neurosci 34:27-33
Greene, Daniel G; Traylor, Steven J; Guo, Jing et al. (2018) Mechanisms of precipitate formation during the purification of an Fc-fusion protein. Biotechnol Bioeng 115:2489-2503
Hilzinger, Jacob M; Raman, Vidhyavathi; Shuman, Kevin E et al. (2018) Differential RNA Sequencing Implicates Sulfide as the Master Regulator of S0 Metabolism in Chlorobaculum tepidum and Other Green Sulfur Bacteria. Appl Environ Microbiol 84:
Allgood, Samual C; Neunuebel, M Ramona (2018) The recycling endosome and bacterial pathogens. Cell Microbiol 20:e12857
Franke, Karl R; Schmidt, Skye A; Park, Sunhee et al. (2018) Analysis of Brachypodium miRNA targets: evidence for diverse control during stress and conservation in bioenergy crops. BMC Genomics 19:547

Showing the most recent 10 out of 333 publications