The NM-INBRE DRPP provides critical support for promising new and early career investigators, and is a determining factor in the direction of their developing research careers. These projects address significant biomedical questions and critical health problems in the areas of Brain and Behavioral Health;Cancer;Cardiovascular and Metabolic Diseases;Child Health;Environmental Health;Infectious Disease and Immunity. The quality of the DRPP science is outstanding, resulting in publications in high impact journals, and pending patents for novel pancratistatin and rigidin analogues with anticancer properties. Efforts to encourage research collaboration have been successful, during the current funding period 23% of the publications have involved collaborations between 2 or more NM-INBRE participants, and this trend is expected to increase in the continuing program. Investigators have been successful in competing for external federal grants, in spite of the difficult funding environment, including recent R01, R21, R03, and R15 awards. The DRPP has made significant impacts on the partner institutions, such as San Juan College, a two-year associate degree-granting institution in the four-corners region with a large Native American student population, where the research activity supported by the NM-INBRE was leveraged to justify a competitive application for an NSF grant to remodel the research space and install a clean room that was funded and now supports research projects. The framework of DRPP projects also serve the primary objective of exposing students to research experiences, and this impact will continue with increased opportunities through an expanded portfolio of projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103451-14
Application #
8716088
Study Section
Special Emphasis Panel (ZGM1-TWD-3 (IN))
Project Start
Project End
Budget Start
2014-06-15
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$1,999,007
Indirect Cost
$80,500
Name
New Mexico State University Las Cruces
Department
Type
DUNS #
173851965
City
Las Cruces
State
NM
Country
United States
Zip Code
88003
Gautam, Gayatri P; Gurung, Rubi; Fencl, Frank A et al. (2018) Separation of sub-micron particles from micron particles using acoustic fluid relocation combined with acoustophoresis. Anal Bioanal Chem 410:6561-6571
Brown, Tom; Brown, Nick; Stollar, Elliott J (2018) Most yeast SH3 domains bind peptide targets with high intrinsic specificity. PLoS One 13:e0193128
Joseph, Braveen B; Blouin, Nicolas A; Fay, David S (2018) Use of a Sibling Subtraction Method for Identifying Causal Mutations in Caenorhabditis elegans by Whole-Genome Sequencing. G3 (Bethesda) 8:669-678
He, Jingxuan; Melançon 3rd, Charles E (2018) Genetic Incorporation of Unnatural Amino Acids into Proteins of Interest in Streptomyces venezuelae ATCC 15439. Methods Mol Biol 1728:155-168
Edwards, Leslie; Turner, Danielle; Champion, Cody et al. (2018) Photoactivated 2,3-distyrylindoles kill multi-drug resistant bacteria. Bioorg Med Chem Lett 28:1879-1886
Maslivetc, Vladimir A; Turner, Danielle N; McNair, Kimberly N et al. (2018) Desymmetrization of Cyclopropenes via the Potassium-Templated Diastereoselective 7- exo- trig Cycloaddition of Tethered Amino Alcohols toward Enantiopure Cyclopropane-Fused Oxazepanones with Antimycobacterial Activity. J Org Chem 83:5650-5664
Gautam, Gayatri P; Burger, Tobias; Wilcox, Andrew et al. (2018) Simple and inexpensive micromachined aluminum microfluidic devices for acoustic focusing of particles and cells. Anal Bioanal Chem 410:3385-3394
Martin, David R; LaBauve, Elisa; Pomo, Joseph M et al. (2018) Site-Specific Genomic Alterations in a Well-Differentiated Pancreatic Neuroendocrine Tumor With High-Grade Progression. Pancreas 47:502-510
Rubasinghege, Gayan; Gurung, Rubi; Rijal, Hom et al. (2018) Abiotic degradation and environmental toxicity of ibuprofen: Roles of mineral particles and solar radiation. Water Res 131:22-32
Dotson, Rachel J; Pias, Sally C (2018) Reduced Oxygen Permeability upon Protein Incorporation Within Phospholipid Bilayers. Adv Exp Med Biol 1072:405-411

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