Abstract

BioSpectroscopy Core Research Laboratory (BCRL) Project Summary The BioSpectroscopy Core Research Laboratory (BCRL) supports the research activities of CBSD investigators, integrating its research activities with other CBSD core research facilities (computational, X-ray diffraction), to provide a synergistic and multi-disciplinary approach to address fundamental questions in biophysics, biochemistry, molecular biology and biomedical sciences. The mission of the BCRL is to facilitate the research programs of CBSD investigators and their trainees, and other UM investigators and their trainees, by serving as a collaborative research resource for state-of-the-art time-resolved fluorescence spectroscopy and imaging, as well as single-molecule spectroscopy. The BCRL accomplishes its mission by providing investigators, and their trainees, access to high-end spectroscopy instrumentation, technologies, services, and consultation; by dissemination; and by providing educational training opportunities for graduate students interested in broadening their knowledge of fluorescence theory and techniques in biophysical applications.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103546-06
Application #
9148608
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
6
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
University of Montana
Department
Type
DUNS #
010379790
City
Missoula
State
MT
Country
United States
Zip Code
59812

  Publications

Brust, Richard; Shang, Jinsai; Fuhrmann, Jakob et al. (2018) A structural mechanism for directing corepressor-selective inverse agonism of PPAR?. Nat Commun 9:4687
Day, Nicholas J; Ellenbecker, Mary; Voronina, Ekaterina (2018) Caenorhabditis elegans DLC-1 associates with ribonucleoprotein complexes to promote mRNA regulation. FEBS Lett 592:3683-3695
Gates, Christina; Backos, Donald S; Reigan, Philip et al. (2018) Isoxazolo[3,4-d]pyridazinones positively modulate the metabotropic glutamate subtypes 2 and 4. Bioorg Med Chem 26:4797-4803
Tait Wojno, Elia D; Beamer, Celine A (2018) Isolation and Identification of Innate Lymphoid Cells (ILCs) for Immunotoxicity Testing. Methods Mol Biol 1803:353-370
Chrisman, Ian M; Nemetchek, Michelle D; de Vera, Ian Mitchelle S et al. (2018) Defining a conformational ensemble that directs activation of PPAR?. Nat Commun 9:1794
Anacker, Melissa L; Drecktrah, Dan; LeCoultre, Richard D et al. (2018) RNase III Processing of rRNA in the Lyme Disease Spirochete Borrelia burgdorferi. J Bacteriol 200:
Yi, Feng; Zachariassen, Linda G; Dorsett, Katherine N et al. (2018) Properties of Triheteromeric N-Methyl-d-Aspartate Receptors Containing Two Distinct GluN1 Isoforms. Mol Pharmacol 93:453-467
Sun, Jiyu; Riel, Asia Marie S; Berryman, Orion B (2018) Solvatochromism and fluorescence response of a halogen bonding anion receptor. New J Chem 42:10489-10492
Ellenbecker, Mary; Osterli, Emily; Wang, Xiaobo et al. (2018) Dynein Light Chain DLC-1 Facilitates the Function of the Germline Cell Fate Regulator GLD-1 in Caenorhabditis elegans. Genetics :
Penny, William M; Palmer, Christopher P (2018) Sphingomyelin ability to act as chiral selector using nanodisc electrokinetic chromatography. Chem Phys Lipids 214:11-14

Showing the most recent 10 out of 108 publications