Abstract

The Administrative Core is responsible for a number of important activities related to the COBRE program, including organization ofthe annual symposium, the seed grant program, and communication with the oversight committees (EAC and lAC). Dr. West will direct the Administrative Core and will be responsible for all administrative functions ofthe COBRE program. She will be assisted by the Associate Program Director, Dr. Gillian Air, and a full-time staff assistant who will help manage financial and programmatic aspects ofthe Center. Funds to subsidize the user fees of the research core facilities by Junior Investigators will come from the Administrative Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM103640-01
Application #
8465554
Study Section
Special Emphasis Panel (ZRR1-RI-B (01))
Project Start
2012-08-01
Project End
2017-05-31
Budget Start
2012-08-01
Budget End
2013-05-31
Support Year
1
Fiscal Year
2012
Total Cost
$496,968
Indirect Cost
$165,656

  Institution

Name
University of Oklahoma Norman
Department
Type
DUNS #
848348348
City
Norman
State
OK
Country
United States
Zip Code
73019

  Publications

Hebdon, Skyler D; Menon, Smita K; Richter-Addo, George B et al. (2018) Regulatory Targets of the Response Regulator RR_1586 from Clostridioides difficile Identified Using a Bacterial One-Hybrid Screen. J Bacteriol 200:
Cruz-Reyes, Jorge; Mooers, Blaine H M; Doharey, Pawan K et al. (2018) Dynamic RNA holo-editosomes with subcomplex variants: Insights into the control of trypanosome editing. Wiley Interdiscip Rev RNA 9:e1502
Booe, Jason M; Warner, Margaret L; Roehrkasse, Amanda M et al. (2018) Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists. Mol Pharmacol 93:355-367
Muthuramalingam, Meenakumari; White, John C; Murphy, Tamiko et al. (2018) The toxin from a ParDE toxin-antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti-gyrase antibiotics. Mol Microbiol :
Roehrkasse, Amanda M; Booe, Jason M; Lee, Sang-Min et al. (2018) Structure-function analyses reveal a triple ?-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design. J Biol Chem 293:15840-15854
Terzyan, Simon S; Cook, Paul F; Heroux, Annie et al. (2017) Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation. Protein Sci 26:1196-1205
Guillen, Katrin P; Ruben, Eliza A; Virani, Needa et al. (2017) Annexin-directed ?-glucuronidase for the targeted treatment of solid tumors. Protein Eng Des Sel 30:85-94
Vazquez Reyes, Carolina; Tangprasertchai, Narin S; Yogesha, S D et al. (2017) Nucleic Acid-Dependent Conformational Changes in CRISPR-Cas9 Revealed by Site-Directed Spin Labeling. Cell Biochem Biophys 75:203-210
Van Orden, Mason J; Klein, Peter; Babu, Kesavan et al. (2017) Conserved DNA motifs in the type II-A CRISPR leader region. PeerJ 5:e3161
Murugan, Karthik; Babu, Kesavan; Sundaresan, Ramya et al. (2017) The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit. Mol Cell 68:15-25

Showing the most recent 10 out of 47 publications