In this application, the Administrative and Mentoring Core, directed by Dr. Mariana Gerschenson, the COBRE PI, has designed strategies for administering the COBRE-Diabetes and its resources to enhance and accelerate the development of the institution and the JABSOM research capacity on the theme of Diabetes and Insulin Resistance (I/R). The overall goal of this Core is to further a multi-disciplinary diabetes and I/R research center that will develop adequate research capabilities to obtain extramural grant support for its future development. The particular emphasis of the Administrative Core is the coordination of resources to mentor four Junior Investigators and to support the creation of a multi-faceted center that includes a strong component of translational research. First, the Administrative Core will recruit and arrange visits for an External Advisory Committee (EAC) that will both advise and assess the COBRE. Second, the Core will coordinate the development of an individual mentoring plan for each of the four Junior Investigators. The cornerstone of the mentoring plan will be a tailored Mentoring Team for each Junior Investigator with one or more internal primary mentor(s) for scientific and career development, one or more external mentor(s) for scientific collaboration and mentoring, and the COBRE PI. The mentoring team and the Junior Investigator?s progress will be closely monitored by the EAC. Third, we will establish a Pilot Project Program to stimulate and advance extramural funding of diabetes-related proposals from investigators throughout our State.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM113134-03
Application #
9774122
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2019-08-01
Budget End
2020-07-31
Support Year
3
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Bauer, Carolin; le Saux, Olivier; Pomozi, Viola et al. (2018) Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation. Sci Rep 8:5812
Lee, Ryan W Y; Corley, Michael J; Pang, Alina et al. (2018) A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder. Physiol Behav 188:205-211
Kauffenstein, Gilles; Yegutkin, Gennady G; Khiati, Salim et al. (2018) Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum. J Invest Dermatol 138:1862-1870
Shiozawa, Kazue; Watanabe, Manabu; Ikehara, Takashi et al. (2018) Efficacy of intra-arterial contrast-enhanced ultrasonography during transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma. World J Hepatol 10:95-104
Geffner, Mitchell E; Patel, Kunjal; Jacobson, Denise L et al. (2018) Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents. AIDS 32:613-622
Chang, Sandra P; Chun, Maria; Guerrero, Anthony et al. (2018) Medical School Hotline: School of Medicine Departments - Year in Review 2017, Part 2. Hawaii J Med Public Health 77:35-37
Panee, Jun; Gerschenson, Mariana; Chang, Linda (2018) Associations Between Microbiota, Mitochondrial Function, and Cognition in Chronic Marijuana Users. J Neuroimmune Pharmacol 13:113-122
Hulgan, Todd; Ramsey, Benjamin S; Koethe, John R et al. (2018) Relationships between Adipose Mitochondrial Function, Serum Adiponectin, and Insulin Resistance in Persons with HIV after 96 weeks of Antiretroviral Therapy. J Acquir Immune Defic Syndr :
Gong, Ting; Torres, Daniel J; Berry, Marla J et al. (2018) Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins. Free Radic Biol Med 127:172-181
Alfulaij, Naghum; Meiners, Franziska; Michalek, Justin et al. (2018) Cannabinoids, the Heart of the Matter. J Am Heart Assoc 7:

Showing the most recent 10 out of 27 publications