The advent of anti-retroviral nnedications, introduction of highly active anti-retroviral therapy (HAART), and advances in treatment options have transformed HIV disease from an acute terminal disease to a chronic manageable disease. These life-extending treatments can reduce the morbidity and mortality associated with the disease among persons living with HIV/AIDS (PLWHA). Engagement in care is vital for HIV treatment success at both the individual and population levels.^ Although financial barriers to seeking HIV care have been reduced through mechanisms such as the Ryan White Act, a large subset of PLWHA does not remain in 1 2 care. Identifying personal, organizational, and environmental factors that influence patterns of utilization of HIV care among PLWHA is critical to developing strategies to increase initiation of care among them, those who are not in care and retention, and those who have episodic patterns of care utilization. The goal of the HIV care research project is to work with a local community to identify and document psychosocial, cultural, and structural barriers that deter PLWHA in a rural, majority African-American, southern South Carolina (SC) county from initiating and continuing HIV care. Findings of this study will inform development of a pilot, community-initiated intervention to improve initiation and continuation of HIV care among PLWHA.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD001770-08
Application #
8579993
Study Section
Special Emphasis Panel (ZMD1-PA (01))
Project Start
2005-09-30
Project End
2015-02-28
Budget Start
2012-03-19
Budget End
2013-02-28
Support Year
8
Fiscal Year
2012
Total Cost
$186,418
Indirect Cost
$48,562
Name
University of South Carolina at Columbia
Department
Type
DUNS #
041387846
City
Columbia
State
SC
Country
United States
Zip Code
29208
Wigfall, Lisa T; Bynum Mph, Shalanda A; Friedman, Daniela B et al. (2017) Patient-provider communication with HIV-positive women about abnormal Pap test results. Women Health 57:19-39
Tomar, Swati; Graves, Christian A; Altomare, Diego et al. (2016) Human papillomavirus status and gene expression profiles of oropharyngeal and oral cancers from European American and African American patients. Head Neck 38 Suppl 1:E694-704
Spiryda, Lisa Beth; Whitaker, Kara M; Messersmith, Amy et al. (2016) Clinical Utility of Molecular Biomarkers in Cervical Squamous Intraepithelial Lesions in a Young Adult Population. J Low Genit Tract Dis 20:26-30
Anderson, Erin L; Banister, Carolyn E; Kassler, Susannah et al. (2016) Human Papillomavirus Type 16 L2 DNA Methylation in Exfoliated Cervical Cells From College-Age Women. J Low Genit Tract Dis 20:332-7
Wilson, Sacoby; Burwell-Naney, Kristen; Jiang, Chengsheng et al. (2015) Assessment of sociodemographic and geographic disparities in cancer risk from air toxics in South Carolina. Environ Res 140:562-8
Banister, Carolyn E; Messersmith, Amy R; Cai, Bo et al. (2015) Disparity in the persistence of high-risk human papillomavirus genotypes between African American and European American women of college age. J Infect Dis 211:100-8
Xu, Hanwen; Pirisi, Lucia; Creek, Kim E (2015) Six1 overexpression at early stages of HPV16-mediated transformation of human keratinocytes promotes differentiation resistance and EMT. Virology 474:144-53
Rice, LaShanta J; Brandt, Heather M; Hardin, James W et al. (2015) Exploring perceptions of cancer risk, neighborhood environmental risks, and health behaviors of blacks. J Community Health 40:419-30
Graves, Christian A; Jones, Ashley; Reynolds, Justin et al. (2015) Neuroendocrine Merkel cell carcinoma is associated with mutations in key DNA repair, epigenetic and apoptosis pathways: a case-based study using targeted massively parallel sequencing. Neuroendocrinology 101:112-9
Bellinger, Jessica D; Millegan, Whitney; Abdalla, Azza E (2015) ""I'm not ashamed to talk on it!"": African-American women's decisions about cervical cancer prevention and control in South Carolina. Womens Health Issues 25:120-7

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